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头孢曲松与头孢唑林敏感性作为肠杆菌科细菌中头孢泊肟敏感性替代标志物的研究

Ceftriaxone Versus Cefazolin Susceptibility as a Surrogate Marker for Cefpodoxime Susceptibility in Enterobacterales.

作者信息

Lambert Kaitlyn V, Demkowicz Ryan, Murray Amanda, Howard Catessa, Slain Douglas

机构信息

Department of Pharmacy Services, WVU Medicine, Morgantown, West Virginia, USA.

Department of Microbiology, WVU Medicine, Morgantown, West Virginia, USA.

出版信息

Open Forum Infect Dis. 2024 Jul 3;11(7):ofae377. doi: 10.1093/ofid/ofae377. eCollection 2024 Jul.

DOI:10.1093/ofid/ofae377
PMID:39006314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11245689/
Abstract

The Clinical and Laboratory Standards Institute stated that cefpodoxime susceptibility among Enterobacterales can be inferred from cefazolin, but this may overcall cefpodoxime resistance. We report a categorical agreement rate of 64% for cefazolin and 97% for ceftriaxone with cefpodoxime ( = .0001). Ceftriaxone appears to be a more useful cefpodoxime surrogate.

摘要

临床和实验室标准协会指出，肠杆菌科细菌对头孢泊肟的敏感性可从头孢唑林推断得出，但这可能会高估头孢泊肟耐药性。我们报告头孢唑林与头孢泊肟的分类一致率为64%，头孢曲松与头孢泊肟的分类一致率为97%（P = .0001）。头孢曲松似乎是一种更有用的头孢泊肟替代物。

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Int J Med Sci. 2023 Feb 13;20(4):437-443. doi: 10.7150/ijms.80621. eCollection 2023.
2
Antimicrobial Activity of Tebipenem and Comparators against Enterobacterales from diverse Outpatient Centers and Nursing Homes in the United States.替比培南及对照药物对美国不同门诊中心和疗养院肠杆菌科的抗菌活性。
Int J Antimicrob Agents. 2023 Mar;61(3):106733. doi: 10.1016/j.ijantimicag.2023.106733. Epub 2023 Jan 20.
3
Optimizing the Management of Uncomplicated Gram-Negative Bloodstream Infections: Consensus Guidance Using a Modified Delphi Process.优化非复杂性革兰阴性菌血流感染的管理：采用改良德尔菲法的共识指南
Open Forum Infect Dis. 2021 Oct 11;8(10):ofab434. doi: 10.1093/ofid/ofab434. eCollection 2021 Oct.
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Can the Ceftriaxone Breakpoints Be Increased Without Compromising Patient Outcomes?头孢曲松的药敏断点提高会影响患者预后吗？
Open Forum Infect Dis. 2018 Jun 8;5(6):ofy139. doi: 10.1093/ofid/ofy139. eCollection 2018 Jun.
5
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J Med Microbiol. 2015 Oct;64(10):1170-1173. doi: 10.1099/jmm.0.000142. Epub 2015 Jul 23.
6
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