Zaoui Sanaa, Bouelhaz Abdellah, Habchane Amal, Khalouki Hafida, Chait Yassine, Samlani Zouhour, Alioua Ayyoub, Tazi Illias
Department of Pharmacology and Toxicology, Mohammed VI University Hospital, Marrakesh, MAR.
Bioscience and Health Laboratory, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakesh, MAR.
Cureus. 2024 Jun 14;16(6):e62401. doi: 10.7759/cureus.62401. eCollection 2024 Jun.
A generic medication is a copy of an original drug for which the patent has expired. It contains the same active substances and is equivalent in terms of safety, efficacy, and pharmaceutical quality. Generic drugs are produced after the expiration of the brand-name drug's patent, which enables greater competition and reduces costs for patients and healthcare systems. They are subjected to strict regulatory and quality control standards to ensure compliance with pharmaceutical norms. This study aims to determine the current status of generic drug prescribing within the medical departments of the Mohammed VI University Hospital (UH) of Marrakesh. This is a cross-sectional study with descriptive and analytical aims, involving 224 prescriptions issued in the medical departments of the Mohammed VI University Hospital (UH) of Marrakesh. To obtain the data required for the study, we included medical records, prescription sheets, and prescriptions delivered to hospitalized patients. In our study, 224 prescriptions were analyzed, with an overall total of 989 prescribed drugs, and a mean of 4.42 +- 2.39 drugs per prescription. Prescriptions from the Psychiatry Department accounted for 258 (26.09%) of total prescriptions, followed by those from the Cardiology Department at 130 (13.14%) and the Internal Medicine Department at 114 (11.53%). The generic prescribing rate for the UH's medical departments was 403 (40.75%). The Oncology Department had the highest generic prescribing rate (27 (64.29%)), followed by the Infectious Diseases and Rheumatology departments, at 29 (63.04%) and 34 (60.71%), respectively. In contrast, the Psychiatry Department had a generic prescribing rate of just 54 (20.93%). The most frequently prescribed classes as generic drugs were gastric antisecretory agents at 39 (100%), antiemetics at 32 (94.12%), and antivirals at nine (81.82%). The vast majority of drugs, 896 (90.59%), were reimbursable. In conclusion, we have noted that the generic drug prescription rate at the UH remains average compared with other institutions, and needs to be improved to optimize resources and control healthcare costs.
仿制药是专利已过期的原研药的复制品。它含有相同的活性成分，在安全性、有效性和药品质量方面相当。仿制药在品牌药专利过期后生产，这使得竞争更加激烈，并降低了患者和医疗系统的成本。它们受到严格的监管和质量控制标准的约束，以确保符合药品规范。本研究旨在确定马拉喀什穆罕默德六世大学医院（UH）各医疗科室仿制药处方的现状。这是一项具有描述性和分析性目的的横断面研究，涉及马拉喀什穆罕默德六世大学医院（UH）各医疗科室开具的224张处方。为了获取研究所需要的数据，我们纳入了病历、处方单以及提供给住院患者的处方。在我们的研究中，分析了224张处方，总共开具了989种药物，每张处方平均有4.42±2.39种药物。精神科的处方占总处方数的258张（26.09%），其次是心内科的130张（13.14%）和内科的114张（11.53%）。UH各医疗科室的仿制药处方率为403张（40.75%）。肿瘤科的仿制药处方率最高（27张，64.29%），其次是传染病科和风湿科，分别为29张（63.04%）和34张（60.71%）。相比之下，精神科的仿制药处方率仅为54张（20.93%）。最常被开具的仿制药类别是胃抗分泌剂，有39种（100%），止吐药有32种（94.12%），抗病毒药有9种（81.82%）。绝大多数药物，896种（90.59%），是可报销的。总之，我们注意到与其他机构相比，UH的仿制药处方率仍然处于平均水平，需要加以提高以优化资源并控制医疗成本。
