Y.Y. Leung, MBChB, MD, Duke-NUS Medical School, Department of Rheumatology and Immunology, Singapore General Hospital, Singapore;
D.D. Gladman, MD, University of Toronto, Schroeder Arthritis Institute, Krembil Research Institute, Psoriatic Arthritis Program, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada.
J Rheumatol. 2024 Oct 1;51(Suppl 2):80-83. doi: 10.3899/jrheum.2024-0515.
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group provided updates at the GRAPPA 2023 annual meeting on its work to evaluate composite outcome measures for PsA. An ongoing systematic literature review is in progress to evaluate psychometric measurement properties using the OMERACT filter 2.2 for a list of candidate composite outcome measures, which include minimal disease activity (MDA), Disease Activity for Psoriatic Arthritis (DAPSA), American College of Rheumatology (ACR) response criteria, Psoriatic Arthritis Disease Activity Score (PASDAS), Composite Psoriatic Disease Activity Index (CPDAI), 3 visual analog scale (3VAS), and 4VAS. The performance of the 3VAS and 4VAS in clinical practice and a synthesis of new data were presented, including estimates for minimal clinically important differences and thresholds of meaning, discrimination and construct validity, and longitudinal construct validity. Numeric rating scale (NRS) versions of the VAS have also been tested. Performance characteristics and psychometric properties are similar to the ASSESS study, a UK multicenter study, indicating that the VAS scales may be feasible tools for routine clinical care with a preference for the 4VAS because of superior face validity and clinical utility.
银屑病关节炎(PsA)研究和评估小组(GRAPPA)-风湿病结局测量学(OMERACT)工作组在 2023 年 GRAPPA 年会上提供了关于评估 PsA 综合结局测量的最新进展。正在进行一项系统的文献综述,以使用 OMERACT 筛选器 2.2 评估候选综合结局测量的心理测量学测量特性,这些测量包括最小疾病活动(MDA)、银屑病关节炎疾病活动度(DAPSA)、美国风湿病学会(ACR)反应标准、银屑病关节炎疾病活动评分(PASDAS)、综合银屑病疾病活动指数(CPDAI)、3 视觉模拟量表(3VAS)和 4VAS。在临床实践中,3VAS 和 4VAS 的表现以及新数据的综合结果被提出,包括最小临床重要差异和有意义的阈值、区分和结构有效性以及纵向结构有效性的估计值。VAS 的数字评定量表(NRS)版本也已经过测试。性能特征和心理测量特性与英国多中心研究 ASSESS 研究相似,这表明 VAS 量表可能是常规临床护理的可行工具,由于 4VAS 具有更好的表面有效性和临床实用性,因此更受欢迎。