Sutar Ajit A, Dashpute Rohit S, Shinde Yashodhara D, Mukherjee Srestha, Chowdhury Chiranjit
Biochemical Sciences Division, CSIR- National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, MH 411008 India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002 India.
Indian J Microbiol. 2024 Jun;64(2):267-286. doi: 10.1007/s12088-023-01176-4. Epub 2023 Dec 28.
Gastroenteritis caused by non-typhoidal still prevails resulting in several recent outbreaks affecting many people worldwide. The presence of invasive non-typhoidal is exemplified by several characteristic symptoms and their severity relies on prominent risk factors. The persistence of this pathogen can be attributed to its broad host range, complex pathogenicity and virulence and adeptness in survival under challenging conditions inside the host. Moreover, a peculiar aid of the ever-changing climatic conditions grants this organism with remarkable potential to survive within the environment. Abusive use of antibiotics for the treatment of gastroenteritis has led to the emergence of multiple drug resistance, making the infections difficult to treat. This review emphasizes the importance of early detection of , along with strategies for accomplishing it, as well as exploring alternative treatment approaches. The exceptional characteristics exhibited by like strategies of infection, persistence, and survival parallelly with multiple drug resistance, make this pathogen a prominent concern to human health.
非伤寒型[病原体名称未明确,推测为细菌之类]引起的肠胃炎仍然普遍存在,导致近期发生了几起影响全球许多人的疫情爆发。侵袭性非伤寒型[同前]的存在表现为几种特征性症状,其严重程度取决于突出的风险因素。这种病原体的持续存在可归因于其广泛的宿主范围、复杂的致病性和毒力以及在宿主内具有挑战性的条件下生存的能力。此外,不断变化的气候条件的特殊助力赋予这种生物体在环境中显著的生存潜力。滥用抗生素治疗肠胃炎导致了多重耐药性的出现,使感染难以治疗。本综述强调了早期检测[同前]的重要性,以及实现早期检测的策略,同时探索替代治疗方法。[同前]所展现出的特殊特征,如感染、持续存在和生存策略以及多重耐药性,使这种病原体成为人类健康的一个突出关注点。