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小儿肝移植。第二部分。术后管理中的诊断性影像学检查。

Pediatric liver transplantation. Part II. Diagnostic imaging in postoperative management.

作者信息

Dominguez R, Young L W, Ledesma-Medina J, Cienfuegos J, Gartner J C, Bron K M, Starzl T E

出版信息

Radiology. 1985 Nov;157(2):339-44. doi: 10.1148/radiology.157.2.3901104.

Abstract

The postoperative diagnostic imaging examinations of 44 children who underwent 59 orthotopic liver transplantations were reviewed. The imaging modalities used for the evaluation of suspected complications include plain roentgenography, ultrasonography (US), computed tomography (CT), nuclear scintigraphy, arteriography, percutaneous and operative cholangiography, and endoscopic retrograde cholangiopancreatography. The main postoperative complications included ischemia, thrombosis (hepatic artery and portal vein), infarction, obstruction or leakage of the biliary anastomosis, hepatic and perihepatic infection, and allograft rejection. US, the most frequently used abdominal imaging modality, was best suited for detection of biliary duct dilatation, fluid collections in or around the transplanted liver, and hepatic arterial, inferior vena caval, and portal vein thrombosis. CT was especially helpful in corroborating findings of infection and in locating abscesses. Technetium 99m sulfur colloid (early- and late-phase imaging) provided a sensitive, although nonspecific, means of assessing allograft vascularization and morphology. Angiography showed vascularity most clearly, and cholangiography was the most useful in the assessment of bile duct patency. A diagnostic imaging algorithm is proposed for evaluation of suspected complications.

摘要

回顾了44例接受59次原位肝移植的儿童的术后诊断性影像学检查。用于评估疑似并发症的成像方式包括普通X线摄影、超声检查(US)、计算机断层扫描(CT)、核素显像、动脉造影、经皮和手术胆管造影以及内镜逆行胰胆管造影。主要的术后并发症包括缺血、血栓形成(肝动脉和门静脉)、梗死、胆肠吻合口梗阻或漏、肝和肝周感染以及同种异体移植排斥反应。US是最常用的腹部成像方式,最适合检测胆管扩张、移植肝内或周围的液体积聚以及肝动脉、下腔静脉和门静脉血栓形成。CT在证实感染发现和定位脓肿方面特别有帮助。锝99m硫胶体(早期和晚期成像)提供了一种敏感但非特异性的评估同种异体移植血管化和形态的方法。血管造影最清楚地显示血管情况,胆管造影在评估胆管通畅性方面最有用。提出了一种用于评估疑似并发症的诊断性成像算法。

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本文引用的文献

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Liver transplantation with use of cyclosporin a and prednisone.使用环孢素A和泼尼松进行肝移植。
N Engl J Med. 1981 Jul 30;305(5):266-9. doi: 10.1056/NEJM198107303050507.
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Evolution of liver transplantation.肝移植的发展历程。
Hepatology. 1982 Sep-Oct;2(5):614-36. doi: 10.1002/hep.1840020516.

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