Shi Shaoyan, Ou Xuehai, Du Xiaolong
Honghui Hospital, Xi'an Jiaotong University, Xi'an, China.
Front Neurol. 2024 Jul 1;15:1370316. doi: 10.3389/fneur.2024.1370316. eCollection 2024.
To evaluate the effect of low-frequency pulse electrical stimulation plus exercise therapy on nerve function recovery in patients with radial nerve palsy after humerus shaft fracture.
A total of 110 patients with humerus shaft fracture and radial nerve injury admitted to our hospital from January 2017 to December 2021 were recruited. They were randomized to receive either conventional exercise therapy (control group) or conventional exercise therapy plus low-frequency pulse electrical stimulation (study group) according to the random number table method, with 55 cases in each. Clinical efficacy, muscle strength recovery, nerve conduction velocity (MCV), amplitude, wrist joint, and elbow joint activities of patients were analyzed and compared.
Patients with low frequency stimulation (LFS) showed significantly higher treatment effectiveness (89.09%) than those with exercise therapy only (69.09%). The incorporation of LFS with exercise therapy provided more enhancement in the muscle strength of wrist extensor and total finger extensor in patients when compared with a mere exercise intervention, suggesting better muscle function recovery of patients produced by LFS. Moreover, a significant increase in MCV and its amplitude was observed in all included patients, among which those receiving LFS showed a greater escalation of MCV and its amplitude. Following a treatment duration of 6 months, more patients in the LFS cohort were reported to achieve a wrist extension and elbow extension with an angle over 45° than the controls. There was no notable variance in adverse responses noted between the two patient groups.
In patients afflicted with humerus shaft fracture and radial nerve injury, the amalgamation of exercise therapy with low-frequency pulse electrical stimulation can significantly improve clinical efficacy, promote nerve function, and muscle strength recovery, and features a high safety profile.
The combination of exercise therapy and low-frequency pulsed electrical stimulation can notably improve the promotion of neurologic function and muscle strength recovery in patients with humerus shaft fractures and radial nerve injuries with a high degree of safety.https://www.researchregistry.com, identifier researchregistry9461.
评估低频脉冲电刺激联合运动疗法对肱骨干骨折后桡神经麻痹患者神经功能恢复的影响。
选取2017年1月至2021年12月我院收治的110例肱骨干骨折合并桡神经损伤患者。根据随机数字表法将其随机分为接受传统运动疗法的对照组和接受传统运动疗法加低频脉冲电刺激的研究组，每组55例。分析比较患者的临床疗效、肌力恢复情况、神经传导速度（MCV）、波幅、腕关节和肘关节活动度。
低频刺激患者的治疗有效率（89.09%）显著高于单纯运动疗法患者（69.09%）。与单纯运动干预相比，低频刺激联合运动疗法能更有效地增强患者腕伸肌和总指伸肌的肌力，提示低频刺激能更好地促进患者肌肉功能恢复。此外，所有纳入患者的MCV及其波幅均显著增加，其中接受低频刺激的患者MCV及其波幅升高幅度更大。治疗6个月后，低频刺激组实现腕关节伸展和肘关节伸展角度超过45°的患者多于对照组。两组患者的不良反应无明显差异。
对于肱骨干骨折合并桡神经损伤患者，运动疗法与低频脉冲电刺激联合应用可显著提高临床疗效，促进神经功能和肌力恢复，且安全性高。
运动疗法和低频脉冲电刺激联合应用可显著提高肱骨干骨折合并桡神经损伤患者的神经功能和肌力恢复，安全性高。https://www.researchregistry.com，标识符researchregistry9461。
