Joly-Kukla Charlotte, Bernard Célia, Bru David, Galon Clémence, Giupponi Carla, Huber Karine, Jourdan-Pineau Hélène, Malandrin Laurence, Rakotoarivony Ignace, Riggi Camille, Vial Laurence, Moutailler Sara, Pollet Thomas
ASTRE, Univ Montpellier, CIRAD, INRAE, Montpellier, France.
ANSES, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, France.
Microbiol Spectr. 2024 Aug 6;12(8):e0125624. doi: 10.1128/spectrum.01256-24. Epub 2024 Jul 16.
is an invasive tick species recently established in mainland southern France. This tick is known to host a diverse range of human and animal pathogens. While information about the dynamics of these pathogens is crucial to assess disease risk and develop effective monitoring strategies, few data on the spatial dynamics of these pathogens are currently available. We collected ticks in 27 sites in the Occitanie region to characterize spatial patterns of -borne pathogens. Several pathogens have been detected: (9.2%), (0.2%), (1.6%), (0.8%), and (87.3%). Interestingly, we found a spatial clustered distribution for the pathogen between two geographically isolated areas with infection rates and bacterial loads significantly lower in Hérault/Gard departments (infection rate 78.6% in average) compared to Aude/Pyrénées-Orientales departments (infection rate 92.3% in average). At a smaller scale, infection rates varied from one site to another, ranging from 29% to 100%. Overall, such high infection rates (87.3% on average) and the effective maternal transmission of might suggest a role as a tick symbiont in . Further studies are thus needed to understand both the status and the role of in ticks.IMPORTANCETicks are obligatory hematophagous arthropods that transmit pathogens of medical and veterinary importance. Pathogen infections cause serious health issues in humans and considerable economic loss in domestic animals. Information about the presence of pathogens in ticks and their dynamics is crucial to assess disease risk for public and animal health. Analyzing tick-borne pathogens in ticks collected in 27 sites in the Occitanie region, our results highlight clear spatial patterns in the -borne pathogen distribution and strengthen the postulate that it is essential to develop effective monitoring strategies and consider the spatial scale to better characterize the circulation of tick-borne pathogens.
是一种最近在法国南部大陆定殖的侵袭性蜱种。已知这种蜱携带多种人类和动物病原体。虽然关于这些病原体动态的信息对于评估疾病风险和制定有效的监测策略至关重要，但目前关于这些病原体空间动态的数据很少。我们在奥克西塔尼地区的27个地点采集了蜱，以表征蜱传播病原体的空间模式。检测到了几种病原体：（9.2%），（0.2%），（1.6%），（0.8%），以及（87.3%）。有趣的是，我们发现病原体在两个地理上隔离的区域之间呈空间聚集分布，与奥德/东比利牛斯省（平均感染率92.3%）相比，埃罗省/加尔省的感染率和细菌载量显著较低（平均感染率78.6%）。在较小尺度上，感染率因地点而异，范围从29%到100%。总体而言，如此高的感染率（平均87.3%）以及的有效母系传播可能表明在蜱中作为蜱共生体发挥作用。因此，需要进一步研究以了解在蜱中的状态和作用。重要性蜱是 obligatory hematophagous 节肢动物，传播具有医学和兽医学重要性的病原体。病原体感染在人类中导致严重的健康问题，在家畜中造成相当大的经济损失。关于蜱中病原体的存在及其动态的信息对于评估公共和动物健康的疾病风险至关重要。通过分析在奥克西塔尼地区27个地点采集的蜱中的蜱传播病原体，我们的结果突出了蜱传播病原体分布中的明显空间模式，并强化了这样的假设，即制定有效的监测策略并考虑空间尺度以更好地表征蜱传播病原体的传播至关重要。 （注：原文中“obligatory hematophagous”可能有误，推测可能是“obligate hematophagous”，意为专性吸血的 ）
