Thomas P, Mura P, Tallineau C, Bounaud M P, Reiss D, Bontoux D
Rev Rhum Mal Osteoartic. 1985 Jun;52(6):381-3.
Urinary neopterin was assayed by HPLC (high performance liquid chromatography). 75 assays were performed in a population of 21 patients with multiple myeloma. There was a significant correlation between the urinary neopterin level and the electrophoretic peak, the R beta-2 microglobulinaemia ratio and the calculated tumour mass (Tbmc). This study demonstrates the value of this assay in the monitoring of patients with multiple myeloma.
采用高效液相色谱法（HPLC）检测尿新蝶呤。对21例多发性骨髓瘤患者群体进行了75次检测。尿新蝶呤水平与电泳峰、Rβ2微球蛋白血症比率及计算得出的肿瘤质量（Tbmc）之间存在显著相关性。本研究证明了该检测方法在监测多发性骨髓瘤患者中的价值。
