Crausaz F, Bischof-Delaloye A, Cretin T, Delaloye B, Gonvers J J, Favez G
Schweiz Med Wochenschr. 1985 Jul 20;115(29):994-5.
Although the relationship between chronic bronchopathies and gastro-esophageal reflux is known, the existence and role of nocturnal broncho-aspiration is controversial. 32 patients with chronic bronchopathy and 13 controls without digestive or respiratory symptoms were studied. Nocturnal broncho-aspiration was diagnosed by the demonstration of vegetable fibers in the morning expectorate and by the presence of radioactive pulmonary foci 15 hours following an isotopic meal. Vegetable fibers were found with equal frequency in both groups. On the other hand, positive pulmonary scintigraphy, reflecting nocturnal broncho-aspiration, was observed in 24 of the 32 patients (75%) and only in 2 of the 13 controls (15%) (p less than 0.001). Thus, broncho-aspiration is a frequent occurrence in chronic bronchopathies.
尽管慢性支气管疾病与胃食管反流之间的关系已为人所知,但夜间支气管吸入的存在及其作用仍存在争议。对32例慢性支气管疾病患者和13例无消化或呼吸道症状的对照者进行了研究。通过早晨咳出物中发现植物纤维以及同位素餐后15小时出现放射性肺病灶来诊断夜间支气管吸入。两组中发现植物纤维的频率相同。另一方面,反映夜间支气管吸入的阳性肺闪烁显像在32例患者中的24例(75%)中观察到,而在13例对照者中仅2例(15%)观察到(p<0.001)。因此,支气管吸入在慢性支气管疾病中很常见。