通过肉桂酸与磺酰叠氮化物/-对甲苯磺酰甲基异腈/β-酮砜的脱羧磺酰化反应实现可见光诱导的乙烯基砜的合成。
Visible-Light-Induced Synthesis of Vinyl Sulfones via Decarboxylative Sulfonylation of Cinnamic Acids Using Sulfonylazides/-Toluenesulfonylmethyl Isocyanide/β-Keto Sulfones.
作者信息
Ishu Km, Kumar Mahesh, Singh Krishna Nand
机构信息
Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 221005, India.
出版信息
J Org Chem. 2024 Aug 2;89(15):10919-10928. doi: 10.1021/acs.joc.4c01252. Epub 2024 Jul 16.
An efficient visible-light-induced synthesis of vinyl sulfones has been accomplished via decarboxylative sulfonylation of cinnamic acids using sulfonylazides, -toluenesulfonylmethyl isocyanide, and β-keto sulfones as sulfonyl source, in the presence of inexpensive organic photocatalysts like rhodamine B and eosin Y. The reaction is facile, straightforward, and endowed with wide substrate scope and functional group tolerability.
通过使用磺酰叠氮化物、对甲苯磺酰甲基异腈和β-酮砜作为磺酰源，在罗丹明B和曙红Y等廉价有机光催化剂存在下，对肉桂酸进行脱羧磺酰化反应，实现了乙烯基砜的高效可见光诱导合成。该反应简便、直接，具有广泛的底物范围和官能团耐受性。
Zotero 插件