Zhang Lianming, Xiao Jiaxi, Xu Xuemei, Li Kaiting, Li Dan, Li Jianping
Guangxi Key Laboratory of Electrochemical and Magnetochemical Functional Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, China.
Crit Rev Anal Chem. 2024 Jul 16:1-20. doi: 10.1080/10408347.2024.2376233.
Chirality represents a fundamental attribute within living systems and is a pervasive phenomenon in the natural world. The identification and analysis of chiral materials within natural environments and biological systems hold paramount importance in clinical, chemical, and biological sciences. Within chiral analysis, there is a burgeoning focus on developing chiral sensors exhibiting exceptional selectivity, sensitivity, and stability, marking it as a forefront area of research. In the past decade (2013-2023), approximately 1990 papers concerning the application of various chiral materials in chiral sensors have been published. Biological materials and nanomaterials have important applications in the development of chiral sensors, which accounting for 26.67% and 45.24% of the material-related applications in these sensors, respectively; moreover, the development of chiral nanomaterials is closely related to the development of portable and stable chiral sensors. Natural chiral materials, utilized as selective recognition units, are combined with carriers characterized by good physical and chemical properties through functionalization to form various functional chiral materials, which improve the recognition efficiency of chiral sensors. In this article, from the perspective of biological materials, polymer materials, nanomaterials, and other functional chiral materials, the applications of chiral sensors are summarized and the research prospects of chiral sensors are discussed.
手性是生命系统的一个基本属性，也是自然界中普遍存在的现象。在自然环境和生物系统中识别和分析手性物质在临床、化学和生物科学中至关重要。在手性分析领域，开发具有卓越选择性、灵敏度和稳定性的手性传感器正成为一个新兴的研究重点，这使其成为前沿研究领域。在过去十年（2013 - 2023年），大约发表了1990篇关于各种手性材料在手性传感器中应用的论文。生物材料和纳米材料在手性传感器的开发中具有重要应用，分别占这些传感器中与材料相关应用的26.67%和45.24%；此外，手性纳米材料的发展与便携式和稳定的手性传感器的发展密切相关。天然手性材料作为选择性识别单元，通过功能化与具有良好物理和化学性质的载体相结合，形成各种功能性手性材料，提高了手性传感器的识别效率。本文从生物材料、高分子材料、纳米材料等功能性手性材料的角度，对手性传感器的应用进行了总结，并对手性传感器的研究前景进行了探讨。
