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美国移植外科学会常温区域灌注标准:伦理、法律和操作一致性。

American Society of Transplant Surgeons Normothermic Regional Perfusion Standards: Ethical, Legal, and Operational Conformance.

机构信息

Division of Abdominal Transplantation, Baylor University Medical Center, Dallas, TX.

Division of Abdominal Transplantation, University of Nebraska, Omaha, NE.

出版信息

Transplantation. 2024 Aug 1;108(8):1655-1659. doi: 10.1097/TP.0000000000005115. Epub 2024 Jul 17.

Abstract

BACKGROUND

The American Society of Transplant Surgeons convened a multidisciplinary working group to address operational, ethical, and legal considerations surrounding normothermic regional perfusion (NRP) procurement.

METHODS

The working group, comprising members from American Society of Transplant Surgeons and AST across various disciplines including transplant surgery, hepatology, critical care, and bioethics, collaborated to formulate recommendations and guidance for NRP procurement.

RESULTS

The following topics were identified by the group as essential standards that need to be addressed for ethical, legal, and operational conformance: terminology; conceptualization of death in the context of NRP; and communication, logistics, and training and competency.

CONCLUSIONS

Fourteen recommendations that support the ethical and legal acceptability of NRP in the United States and set expectations for the conduct of NRP procedures are provided.

摘要

背景

美国移植外科学会召集了一个多学科工作组,以解决常温区域性灌注(NRP)采集的操作、伦理和法律问题。

方法

工作组由来自美国移植外科学会和 AST 的成员组成,成员来自移植外科、肝脏病学、重症监护和生物伦理学等多个学科,合作制定了 NRP 采集的建议和指南。

结果

工作组确定了以下作为伦理、法律和操作合规性必须解决的基本标准:术语;NRP 背景下的死亡概念化;以及沟通、物流和培训及能力。

结论

提供了 14 项建议,支持美国 NRP 的伦理和法律可接受性,并为 NRP 程序的进行设定了预期。

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