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病例报告:登革热进展为急性肝衰竭和肝性脑病。

Case Report: Dengue Fever Progressing to Acute Liver Failure and Hepatic Encephalopathy.

机构信息

Department of General Medicine, Mahatma Gandhi Memorial Medical College, Indore, India.

Department of General Medicine, All India Institute Of Medical Sciences, Bhopal, India.

出版信息

Am J Trop Med Hyg. 2024 Jul 16;111(3):603-605. doi: 10.4269/ajtmh.23-0516. Print 2024 Sep 4.

Abstract

Dengue fever is an important arboviral disease that significantly impacts the disease burden among populations residing in tropical regions. Dengue infection is known to have a broad spectrum of clinical manifestations, which range from fatal, life-threatening shock, encephalitis, and myocarditis to asymptomatic illness. Mild hepatic dysfunction with deranged hepatic laboratory parameters is a known entity with dengue fever. However, dengue presenting as acute liver failure associated with hepatic encephalopathy without shock or signs of plasma leakage is rare. Therefore, we are reporting the case of a young male with dengue fever presented as acute liver failure from a tertiary care center in central India to spread awareness among healthcare professionals worldwide regarding unusual presentations of dengue fever and consideration of dengue fever as a differential diagnosis in patients presenting with acute liver failure, especially in endemic regions.

摘要

登革热是一种重要的虫媒病毒性疾病,对居住在热带地区的人群的疾病负担有重大影响。已知登革热感染具有广泛的临床表现,从轻症、无生命危险的休克、脑炎和心肌炎到无症状感染不等。登革热伴有肝实验室参数异常的轻度肝功能障碍是已知的病症。然而,登革热表现为无休克或血浆渗漏迹象的急性肝衰竭伴肝性脑病则较为罕见。因此,我们报告了一例来自印度中部一家三级护理中心的年轻男性登革热患者,其表现为急性肝衰竭,旨在提高全球医疗保健专业人员对登革热不常见表现的认识,并考虑将登革热作为急性肝衰竭患者的鉴别诊断,特别是在流行地区。

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Dengue fever presenting as acute liver failure--a case report.登革热致急性肝衰竭 1 例报告
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本文引用的文献

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Dengue hemorrhagic fever and the liver.登革出血热与肝脏
World J Hepatol. 2021 Dec 27;13(12):1968-1976. doi: 10.4254/wjh.v13.i12.1968.
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Dengue in India.印度登革热疫情。
Indian J Med Res. 2012 Sep;136(3):373-90.
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Clinical Manifestations and Management of Dengue/DHF/DSS.登革热/登革出血热/登革休克综合征的临床表现与管理
Trop Med Health. 2011 Dec;39(4 Suppl):83-7. doi: 10.2149/tmh.2011-S10. Epub 2011 Dec 22.
9
Dengue fever presenting as acute liver failure--a case report.登革热致急性肝衰竭 1 例报告
Asian Pac J Trop Med. 2011 Apr;4(4):323-4. doi: 10.1016/S1995-7645(11)60095-3. Epub 2011 May 29.

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