Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany.
Centre for Global Health, Technical University of Munich, Munich, Germany.
BMJ Open. 2024 Jul 16;14(7):e084734. doi: 10.1136/bmjopen-2024-084734.
Identifying key barriers to accessing quality-assured and affordable antimicrobials among forcibly displaced persons in Uganda, Yemen and Colombia and investigating their (1) utilisation patterns of antibiotics, (2) knowledge about antimicrobial resistance (AMR) and (3) perception of the quality of antimicrobials received.
Pilot cross-sectional survey.
Data were collected from five health facilities in the Kiryandongo refugee settlement (Bweyale, Uganda), three camps for internally displaced persons (IDPs) in the Dar Sad district (Aden, Yemen) and a district with a high population of Venezuelan migrants (Kennedy district, Bogotá, Colombia). Data collection took place between February and May 2021. The three countries were selected due to their high number of displaced people in their respective continents.
South Sudanese refugees in Uganda, IDPs in Yemen and Venezuelan migrants in Colombia.
The most common barriers to access to quality-assured and affordable antimicrobials.
A total of 136 participants were enrolled in this study. Obtaining antimicrobials through informal pathways, either without a doctor's prescription or through family and friends, was common in Yemen (27/50, 54.0%) and Colombia (34/50, 68.0%). In Yemen and Uganda, respondents used antibiotics to treat (58/86, 67.4%) and prevent (39/86, 45.3%) a cold. Knowledge of AMR was generally low (24/136, 17.6%). Barriers to access included financial constraints in Colombia and Uganda, prescription requirements in Yemen and Colombia, and non-availability of drugs in Uganda and Yemen.
Our multicentred research identified common barriers to accessing quality antimicrobials among refugees/IDPs/migrants and common use of informal pathways. The results suggest that knowledge gaps about AMR may lead to potential misuse of antimicrobials. Due to the study's small sample size and use of non-probability sampling, the results should be interpreted with caution, and larger-scale assessments on this topic are needed. Future interventions designed for similar humanitarian settings should consider the interlinked barriers identified.
在乌干达、也门和哥伦比亚的被迫流离失所者中确定获得质量保证和负担得起的抗菌药物的主要障碍,并调查他们(1)抗生素的使用模式、(2)对抗微生物药物耐药性(AMR)的认识和(3)对获得的抗菌药物的质量的看法。
试点横断面调查。
数据来自于基永多戈难民营(布韦莱)的五个卫生设施(乌干达)、达尔萨德区的三个境内流离失所者营地(亚丁)和一个委内瑞拉移民人口众多的地区(波哥大的肯尼迪区)。数据收集于 2021 年 2 月至 5 月之间进行。选择这三个国家是因为它们在各自的大陆上都有大量的流离失所者。
在乌干达的南苏丹难民、在也门的境内流离失所者和在哥伦比亚的委内瑞拉移民。
获得质量保证和负担得起的抗菌药物的最常见障碍。
本研究共纳入 136 名参与者。在也门(27/50,54.0%)和哥伦比亚(34/50,68.0%),通过非正式途径获得抗菌药物,无论是没有医生处方还是通过家人和朋友,都是很常见的。在也门和乌干达,受访者用抗生素治疗(58/86,67.4%)和预防(39/86,45.3%)感冒。对抗微生物药物耐药性的认识普遍较低(24/136,17.6%)。获得抗菌药物的障碍包括哥伦比亚和乌干达的经济限制、也门和哥伦比亚的处方要求、以及乌干达和也门的药物供应不足。
我们的多中心研究确定了难民/境内流离失所者/移民获得优质抗菌药物的常见障碍,以及对非正式途径的常见使用。结果表明,对抗微生物药物耐药性的认识差距可能导致潜在的抗菌药物滥用。由于研究的样本量较小且采用非概率抽样,因此应谨慎解释结果,并且需要对此主题进行更大规模的评估。为类似的人道主义环境设计的未来干预措施应考虑到确定的相互关联的障碍。