Sun Bingqing, Ye Yuhao, Zhao Jing, Zhou Xingtao, Niu Lingling
Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, No. 19 Baoqing Road, Shanghai, 200031, China.
NHC Key laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China.
BMC Ophthalmol. 2024 Jul 16;24(1):289. doi: 10.1186/s12886-024-03546-y.
This study assessed the agreement of ocular parameters of patients with myopia measured using Colombo intraocular lens (IOL) 2 and IOLMaster 700.
Eighty patients (male, 22; average age, 29.14 ± 7.36 years) with myopia (159 eyes) were included in this study in May 2023. The participants' axial length (AXL), central corneal thickness (CCT), lens thickness (LT), white-to-white distance (WTW), front flat (K1), steep (K2), mean (Km) corneal keratometry, astigmatism (Astig), J0 vector, and J45 vector were measured using the IOLMaster 700 and Colombo IOL 2. The measurements from both devices were compared using the generalized estimating equation, correlation analysis, and Bland-Altman plots.
With the Colombo IOL 2, lower values for K2 and J0 (odds ratio [OR] = 0.587, p = 0.033; OR = 0.779, p < 0.0001, respectively), and larger values for WTW, Astig, and J45 (OR = 1.277, OR = 1.482, OR = 1.1, all p < 0.0001) were obtained. All ocular measurements by both instruments showed positive correlations, with AXL demonstrating the strongest correlation (r = 0.9996, p < 0.0001). The intraclass correlation coefficients for AXL and CCT measured by both instruments was 0.999 and 0.988 (both p < 0.0001), and Bland-Altman plot showed 95% limits of agreement (LoA) of -0.078 to 0.11 mm and - 9.989 to 13.486 μm, respectively. The maximum absolute 95% LoA for LT, WTW, K1, K2, and J0 were relatively high, achieving 0.829 mm, 0.717 mm, 0.983 D, 0.948 D, and 0.632 D, respectively.
In young patients with myopia, CCT and AXL measurements obtained with the Colombo IOL 2 and IOLMaster 700 were comparable. However, WTW, LT, corneal refractive power, and astigmatism values could not be used interchangeably in clinical practice.
本研究评估了使用科伦坡人工晶状体（IOL）2和IOLMaster 700测量的近视患者眼部参数的一致性。
2023年5月，本研究纳入了80例近视患者（男性22例；平均年龄29.14±7.36岁）的159只眼睛。使用IOLMaster 700和科伦坡IOL 2测量参与者的眼轴长度（AXL）、中央角膜厚度（CCT）、晶状体厚度（LT）、白对白距离（WTW）、前表面平坦度（K1）、陡峭度（K2）、平均角膜曲率（Km）、散光（Astig）、J0向量和J45向量。使用广义估计方程、相关性分析和Bland-Altman图对两种设备的测量结果进行比较。
使用科伦坡IOL 2时，K2和J0的值较低（优势比[OR]=0.587，p=0.033；OR=0.779，p<0.0001），而WTW、Astig和J45的值较大（OR=1.277、OR=1.482、OR=1.1，均p<0.0001）。两种仪器的所有眼部测量均显示出正相关性，其中AXL的相关性最强（r=0.9996，p<0.0001）。两种仪器测量的AXL和CCT的组内相关系数分别为0.999和0.988（均p<0.0001），Bland-Altman图显示一致性界限（LoA）的95%分别为-0.078至0.11毫米和-9.989至13.486微米。LT、WTW、K1、K2和J0的最大绝对95%LoA相对较高，分别达到0.829毫米、0.717毫米、0.983 D、0.948 D和0.632 D。
在年轻近视患者中，使用科伦坡IOL 2和IOLMaster 700获得的CCT和AXL测量结果具有可比性。然而，WTW、LT、角膜屈光力和散光值在临床实践中不能互换使用。
