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青少年2型糖尿病多学科护理诊所中的健康指标、抑郁症状与社区贫困状况

Health markers, depressive symptoms, and community deprivation in a type 2 diabetes multidisciplinary care clinic for youth.

作者信息

Bejarano Carolina M, Ley Sanita, Krishnan Nisha, Orkin Sarah, Crimmins Nancy A, Schaaf Lisa, Shah Amy S

机构信息

Division of Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

出版信息

Clin Diabetes Endocrinol. 2024 Jul 17;10(1):21. doi: 10.1186/s40842-024-00180-x.

Abstract

INTRODUCTION

Type 2 diabetes disproportionately affects non-Hispanic/Latino Black and Hispanic/Latino youth. The purpose of this study was to examine whether differences in metabolic risk factors and depressive symptoms exist by race/ethnicity and socioeconomic deprivation and whether these impact clinic attendance and health markers over 1 year in a multidisciplinary type 2 diabetes clinic for youth.

METHODS

This study was a retrospective chart review of 54 youth with type 2 diabetes who had both an initial and follow-up visit. Demographic information, metabolic health markers [body mass index (BMI), hemoglobin A1C, liver enzymes, lipid panel, and urine microalbumin], depressive symptoms, and clinic attendance data were obtained from the medical record. Patient address was geocoded to the census tract level to calculate community socioeconomic deprivation.

RESULTS

Liver enzymes (ALT and AST) were significantly higher in patients identifying as Hispanic/Latino (ALT M = 97.0 ± 40.6, AST M = 53.6 ± 21.4) and lowest in patients identifying as non-Hispanic/Latino Black (ALT M = 23.1 ± 11.3, F = 10.6 p < .001; AST M = 23.1 ± 11.4, F = 8.1; p < .001) at initial visit. From initial visit to follow-up, there were significant improvements in ALT (F = 13.43, p < .001), AST (F = 6.58, p < .05), and BMIz (F = 18.39, p < .001). Patients identifying as Black or Hispanic showed an increase in depressive symptoms over time, while patients identifying as non-Hispanic White showed a decrease (F = 11.08; p < .05). Unexpectedly, patients living in areas with higher socioeconomic deprivation showed a decrease in hemoglobin A1C over time, while patients living in lower socioeconomic deprivation showed an increase (F = 5.15, p < .05).

CONCLUSIONS

Differences exist in metabolic health parameters by race/ethnicity and by socioeconomic deprivation. Multidisciplinary care for youth with type 2 diabetes needs to consider and work to address the systems of inequity experienced by patients that drive disparities in health outcomes.

摘要

引言

2型糖尿病对非西班牙裔/拉丁裔黑人及西班牙裔/拉丁裔青少年的影响尤为严重。本研究旨在探讨代谢风险因素和抑郁症状在种族/族裔及社会经济剥夺方面是否存在差异,以及这些因素在为期一年的青少年2型糖尿病多学科诊所中对就诊率和健康指标的影响。

方法

本研究是对54名患有2型糖尿病且进行了初次和随访就诊的青少年进行的回顾性病历审查。从病历中获取人口统计学信息、代谢健康指标[体重指数(BMI)、糖化血红蛋白、肝酶、血脂谱和尿微量白蛋白]、抑郁症状及就诊数据。将患者地址编码到普查区层面以计算社区社会经济剥夺程度。

结果

在初次就诊时,自认为西班牙裔/拉丁裔的患者肝酶(谷丙转氨酶和谷草转氨酶)显著更高(谷丙转氨酶平均值 = 97.0 ± 40.6,谷草转氨酶平均值 = 53.6 ± 21.4),而自认为非西班牙裔/拉丁裔黑人的患者肝酶最低(谷丙转氨酶平均值 = 23.1 ± 11.3,F = 10.6,p <.001;谷草转氨酶平均值 = 23.1 ± 11.4,F = 8.1;p <.001)。从初次就诊到随访,谷丙转氨酶(F = 13.43,p <.001)、谷草转氨酶(F = 6.58,p < .05)和BMIz(F = 18.39,p <.001)有显著改善。随着时间推移,自认为黑人或西班牙裔的患者抑郁症状增加,而自认为非西班牙裔白人的患者抑郁症状减少(F = 11.08;p <.05)。出乎意料的是,随着时间推移,生活在社会经济剥夺程度较高地区的患者糖化血红蛋白下降,而生活在社会经济剥夺程度较低地区的患者糖化血红蛋白上升(F = 5.15,p <.05)。

结论

代谢健康参数在种族/族裔及社会经济剥夺方面存在差异。对青少年2型糖尿病的多学科护理需要考虑并努力解决患者所经历的导致健康结果差异的不公平系统问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69ac/11253452/4feee163306f/40842_2024_180_Fig1_HTML.jpg

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