Carruthers Katherine H, Austen William G, Remy Katya, Hamaguchi Ryoko, Liu Sofia, Vyas Krishna, Bojovic Branko
Aesthet Surg J Open Forum. 2024 Jun 3;6:ojae043. doi: 10.1093/asjof/ojae043. eCollection 2024.
Outcomes following autologous fat grafting have historically been unpredictable because of variability in fat retention rates. The novel poloxamer wash, absorption, mesh filtration system (PWAS) uses proprietary technology to stabilize and concentrate lipoaspirate. Its use in low-volume fat grafting has not been reported.
The authors in this study aimed to compare PWAS technology with traditional lipoaspirate processing techniques in low-volume fat grafting procedures.
Medical charts were reviewed to determine a consecutive cohort of patients who underwent fat grafting for facial feminization. All patients had obtained preoperative and postoperative 3-dimensional facial imaging. Patients were grouped based on the method of lipoaspirate processing. The analysis software was used to measure changes in facial volume, and percent retention was calculated.
Between September 2021 and February 2023, 11 facial fat grafting procedures were performed using the PWAS, and 5 performed using traditional lipoaspirate osmotic filtration with Telfa. Age and BMI were statistically similar between both the groups ( > .1). The average volume of lipoaspirate that was grafted was 23.4 mL (standard deviation [SD] 10.9 mL) and similar between both the groups ( > .1). The mean follow-up duration was 7.1 months (SD 3.1 months): 7.2 months, SD 3.5 months in the PWAS group vs 7.0 months, SD 2.2 months in the osmotic filtration group ( > .5). The average fat volume retention rate was 73.1% (SD 6.8%) in patients in whom the PWAS was used when compared with 46.1% (SD 5.2%) in patients in whom osmotic filtration was used ( > .01).
For patients undergoing low volume fat grafting, the PWAS technology may result in improved fat retention rates when compared with traditional lipoaspirate processing with Telfa.
由于脂肪留存率存在差异，自体脂肪移植的效果历来难以预测。新型泊洛沙姆冲洗、吸收、网状过滤系统（PWAS）采用专有技术来稳定和浓缩脂肪抽吸物。其在小容量脂肪移植中的应用尚未见报道。
本研究的作者旨在比较PWAS技术与传统脂肪抽吸物处理技术在小容量脂肪移植手术中的效果。
回顾病历以确定连续一组接受面部女性化脂肪移植的患者。所有患者均获得术前和术后的三维面部成像。根据脂肪抽吸物处理方法对患者进行分组。使用分析软件测量面部体积变化，并计算留存百分比。
在2021年9月至2023年2月期间，使用PWAS进行了11例面部脂肪移植手术，使用传统的Telfa脂肪抽吸渗透过滤法进行了5例手术。两组患者的年龄和体重指数在统计学上相似（P＞0.1）。移植的脂肪抽吸物平均体积为23.4 mL（标准差[SD]10.9 mL），两组相似（P＞0.1）。平均随访时间为7.1个月（SD 3.1个月）：PWAS组为7.2个月，SD 3.5个月，而渗透过滤组为7.0个月，SD 2.2个月（P＞0.5）。使用PWAS的患者平均脂肪体积留存率为73.1%（SD 6.8%），而使用渗透过滤的患者为46.1%（SD 5.2%）（P＜0.01）。
对于接受小容量脂肪移植的患者，与使用Telfa的传统脂肪抽吸物处理方法相比，PWAS技术可能会提高脂肪留存率。
