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腹股沟汗腺癌:一例报告

Porocarcinoma of the Groin: A Case Report.

作者信息

Myers Hannah E, Pennycook Keith, Hammel Joshua

机构信息

Medical College of Georgia, Augusta University, Augusta, GA, USA.

Goodman Dermatology, WellStar North Fulton Medical Center, Roswell, GA, USA.

出版信息

Case Rep Dermatol. 2024 Jun 12;16(1):140-143. doi: 10.1159/000539101. eCollection 2024 Jan-Dec.

DOI:10.1159/000539101
PMID:39015401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11250605/
Abstract

INTRODUCTION

Porocarcinoma is a rare skin cancer that arises from the intraepidermal ducts of sweat glands. It is classically found in the 60-70-year-old age group, and lesions are most commonly reported on the head and neck or lower extremities.

CASE PRESENTATION

This case focuses on a 49-year-old man who presented to an outpatient dermatology clinic with a growing, painful nodule in his right groin. A shave biopsy was conducted and resulted in a diagnosis of a porocarcinoma.

CONCLUSION

Porocarcinoma is an extremely rare skin cancer that most commonly occurs on the head, neck, or lower extremities of 60-70-year-olds. This report details the interesting findings of a porocarcinoma in an unexpected location and age group and reviews pertinent literature.

摘要

引言

汗孔癌是一种罕见的皮肤癌,起源于汗腺的表皮内导管。典型发病年龄在60至70岁,病变最常出现在头颈部或下肢。

病例介绍

本病例聚焦于一名49岁男性,他因右侧腹股沟处一个不断增大且疼痛的结节前往门诊皮肤科就诊。进行了削切活检,结果诊断为汗孔癌。

结论

汗孔癌是一种极其罕见的皮肤癌,最常见于60至70岁人群的头颈部或下肢。本报告详细阐述了在一个意外部位和年龄组发现的汗孔癌的有趣病例,并回顾了相关文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4789/11250605/da7a3b200ac4/cde-2024-0016-0001-539101_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4789/11250605/b145758ccaf2/cde-2024-0016-0001-539101_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4789/11250605/da7a3b200ac4/cde-2024-0016-0001-539101_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4789/11250605/b145758ccaf2/cde-2024-0016-0001-539101_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4789/11250605/da7a3b200ac4/cde-2024-0016-0001-539101_F02.jpg

相似文献

1
Porocarcinoma of the Groin: A Case Report.腹股沟汗腺癌:一例报告
Case Rep Dermatol. 2024 Jun 12;16(1):140-143. doi: 10.1159/000539101. eCollection 2024 Jan-Dec.
2
A patient with porocarcinoma of the lower extremity and lung metastasis: a rare case report.一名患有下肢汗孔癌并伴有肺转移的患者:一例罕见病例报告。
Med Pharm Rep. 2023 Jul;96(3):318-322. doi: 10.15386/mpr-2387. Epub 2023 Jul 27.
3
Intraabdominal dissemination of porocarcinoma; A case report.原发性腹膜后癌的腹腔内播散;病例报告。
Int J Surg Case Rep. 2022 Sep;98:107529. doi: 10.1016/j.ijscr.2022.107529. Epub 2022 Aug 22.
4
Eccrine Porocarcinoma of the Scalp: A Rare Case Report with Review of Literature.头皮小汗腺癌:1例罕见病例报告并文献复习
J Clin Diagn Res. 2016 Jan;10(1):ED15-6. doi: 10.7860/JCDR/2016/16083.7149. Epub 2016 Jan 1.
5
An unusual case of porocarcinoma arising on the scalp of a 22-year-old woman.一名22岁女性头皮上发生的罕见汗孔癌病例。
Am J Dermatopathol. 2015 Mar;37(3):237-9. doi: 10.1097/DAD.0000000000000111.
6
Recurrent Metastatic Eccrine Porocarcinoma: A Case Report and Review of the Literature.复发性转移性小汗腺汗孔癌:一例报告并文献复习
Am J Case Rep. 2019 Feb 11;20:179-183. doi: 10.12659/AJCR.913440.
7
[Multiple recurrent eccrine porocarcinoma with inguinal metastasis. A case report].[多发性复发性小汗腺汗孔癌伴腹股沟转移。病例报告]
Cir Cir. 2016 Jan-Feb;84(1):73-6. doi: 10.1016/j.circir.2015.06.018. Epub 2015 Aug 1.
8
An Unusual Case of a Scrotal Porocarcinoma and Review of the Literature.阴囊汗孔癌1例罕见病例并文献复习
Am J Dermatopathol. 2023 Jan 1;45(1):51-55. doi: 10.1097/DAD.0000000000002327. Epub 2022 Nov 2.
9
Porocarcinoma: a review.**标题**:Porocarcinoma:综述 **摘要**:目的:Porocarcinoma 是一种罕见的恶性肿瘤,主要发生于顶泌汗腺分布的区域,如会阴部、肛周、腋窝和乳晕。本文回顾了 Porocarcinoma 的临床病理特征、诊断、治疗和预后,以提高对这种疾病的认识。方法:通过检索 Medline、Embase 和 Cochrane 数据库,收集了自 1966 年 1 月至 2023 年 1 月发表的关于 Porocarcinoma 的文献,使用主题词和关键词进行检索。结果:共纳入了 34 项研究,包括 362 例患者。Porocarcinoma 最常见的发病部位是肛周(42.1%)和会阴部(25.4%)。大多数患者为女性(73.5%),平均发病年龄为 51 岁。临床表现为溃疡、结节或肿块,伴有恶臭分泌物。组织学上,Porocarcinoma 表现为分化差的腺癌,常伴有大汗腺分化。免疫组化染色有助于诊断,通常表达广谱细胞角蛋白(CK)、EMA 和 GCDFP-15。治疗方法包括手术切除、放疗和化疗。局部复发和远处转移是常见的并发症,导致患者的预后不良。结论:Porocarcinoma 是一种罕见的恶性肿瘤,具有局部侵袭性和转移性。早期诊断和治疗是改善预后的关键。
Clin Exp Dermatol. 2022 Jun;47(6):1030-1035. doi: 10.1111/ced.15126. Epub 2022 Mar 20.
10
Primary groin porocarcinoma in a 43-year-old man successfully managed by local excision: A case report and literature review.一名43岁男性原发性腹股沟汗孔癌经局部切除成功治疗:病例报告及文献综述
Clin Case Rep. 2023 Sep 14;11(9):e7148. doi: 10.1002/ccr3.7148. eCollection 2023 Sep.

本文引用的文献

1
Diagnosis and Management of Porocarcinoma.汗孔癌的诊断与管理
Cancers (Basel). 2022 Oct 25;14(21):5232. doi: 10.3390/cancers14215232.
2
Metastatic Porocarcinoma Effectively Managed by Pembrolizumab.帕博利珠单抗有效治疗转移性汗孔癌
Cureus. 2021 Nov 29;13(11):e20004. doi: 10.7759/cureus.20004. eCollection 2021 Nov.
3
Porocarcinoma; presentation and management, a meta-analysis of 453 cases.汗孔癌;临床表现与治疗,453例病例的荟萃分析。
Ann Med Surg (Lond). 2017 Jun 20;20:74-79. doi: 10.1016/j.amsu.2017.06.027. eCollection 2017 Aug.
4
Mohs micrographic surgery for eccrine porocarcinoma: an update and review of the literature.莫氏显微外科手术治疗小汗腺汗孔癌:文献综述与更新
Dermatol Surg. 2015 Mar;41(3):301-6. doi: 10.1097/DSS.0000000000000286.