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一名患有下肢汗孔癌并伴有肺转移的患者:一例罕见病例报告。

A patient with porocarcinoma of the lower extremity and lung metastasis: a rare case report.

作者信息

Zein Ahmad Fariz Malvi Zamzam, Luthfi Mohamad, Putro Widyatmiko Arifin, Nurbaiti Nurbaiti

机构信息

Department of Internal Medicine, Waled General Hospital - Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia.

Division of Hematology and Medical Oncology, Department of Internal Medicine, Waled General Hospital - Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia.

出版信息

Med Pharm Rep. 2023 Jul;96(3):318-322. doi: 10.15386/mpr-2387. Epub 2023 Jul 27.

DOI:10.15386/mpr-2387
PMID:37577018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10419686/
Abstract

BACKGROUND

Porocarcinoma is a rare cancer of the developing sweat glands. It often occurs in older adults and frequently affects the head, neck, and extremities. We report a rare case of metastatic porocarcinoma with intriguing approach of the diagnosis and management due to limited resource setting.

CASE REPORT

A 60-year-old man with a history of type 2 diabetes mellitus presented with nodules on the left foot with no palpable lymph node. A chest radiograph revealed multiple coin lesions and histopathological findings were suggestive for porocarcinoma. We assessed the case as a metastatic porocarcinoma in a patient with uncontrolled type 2 diabetes mellitus. Surgery was performed in the initial phase of treatment, consisting of below-knee amputation. The patient refused the planned chemotherapy in the referral hospital and then underwent other modalities of palliative care. He passed away eleven months after the initial diagnosis.

CONCLUSIONS

Metastatic porocarcinoma is a rare oncological case with a challenging approach of the diagnosis and management. High awareness of clinical clues in rare cancer is needed for early diagnosis and prompt treatment, especially in limited resource settings.

摘要

背景

汗腺癌是一种发生于发育中的汗腺的罕见癌症。它常发生于老年人,且经常累及头部、颈部和四肢。我们报告一例罕见的转移性汗腺癌病例,由于资源有限,其诊断和管理方法颇具吸引力。

病例报告

一名60岁的2型糖尿病男性患者,左足部出现结节,未触及淋巴结。胸部X线片显示多个硬币状病灶,组织病理学检查结果提示为汗腺癌。我们将该病例评估为一名2型糖尿病控制不佳患者的转移性汗腺癌。治疗初期进行了手术,包括膝下截肢。患者拒绝了转诊医院计划的化疗,随后接受了其他姑息治疗方式。他在初次诊断后11个月去世。

结论

转移性汗腺癌是一种罕见的肿瘤病例,其诊断和管理颇具挑战性。对于罕见癌症,需要高度警惕临床线索以实现早期诊断和及时治疗,尤其是在资源有限的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/313c04e09fd5/cm-96-318f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/8f6ed3c00815/cm-96-318f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/a35a3e6745c3/cm-96-318f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/6825831298f9/cm-96-318f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/313c04e09fd5/cm-96-318f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/8f6ed3c00815/cm-96-318f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/a35a3e6745c3/cm-96-318f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/6825831298f9/cm-96-318f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1325/10419686/313c04e09fd5/cm-96-318f5.jpg

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Eccrine Porocarcinoma with Zosteriform Metastasis.伴带状疱疹样转移的小汗腺癌
Cureus. 2020 Feb 4;12(2):e6873. doi: 10.7759/cureus.6873.
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