Behzad Hadi, Gharibi Reza, Rezvaniamin Mahmood, Kafashan Setareh, Kamrani Ali
Department of Audiology, Shahid Beheshti University of Medical Science, Tehran, Iran.
Department of ENT, Zahedan University of Medical Science, Zahedan, Iran.
Iran J Otorhinolaryngol. 2024 Jul;36(4):517-525. doi: 10.22038/IJORL.2024.77606.3604.
Meniere's disease is an inner ear disorder not associated with central brain structure involvement. Although the ECochG test has been commonly used to diagnose Meniere's disease recently, it has not demonstrated high sensitivity. Therefore, it is recommended that other complementary tests alongside the ECochG test be used to diagnose Meniere's disease. The SVV test has gained popularity recently for this reason, and in this study, it was decided to use the SVV test in both static and dynamic modes, along with the ECochG test, as a tool for diagnosing Meniere's disease and evaluating its diagnostic features.
The study was conducted on 53 patients with confirmed unilateral Meniere's disease and a normal group. Means were calculated with a 95% confidence interval for the groups, and the corresponding graphs were plotted. Independent t-tests were used to examine the difference in SVV results between the normal and Meniere's groups. The ROC curve was then used to determine the cutoff point and calculate.
After investigating the cutoff point for the three SVV conditions (tilted towards the lesion), a cutoff point of 2.1 degrees with a sensitivity and specificity of approximately 0.7 was identified as the best condition for distinguishing the Meniere's group from the healthy group.
Finally, based on the findings, it can be concluded that the SVV test has relatively low sensitivity for diagnosing Meniere's disease. Therefore, more than relying solely on its results to identify Meniere's disease is required, and it is suggested that other measures alongside the ECochG and SVV tests be included in future studies for further investigation.
梅尼埃病是一种内耳疾病,与中枢脑结构受累无关。尽管耳声发射测试(ECochG)最近已被普遍用于诊断梅尼埃病,但它并未显示出高敏感性。因此,建议在ECochG测试之外使用其他补充测试来诊断梅尼埃病。出于这个原因,主观视觉垂直测试(SVV)最近受到了欢迎,在本研究中,决定将静态和动态模式下的SVV测试与ECochG测试一起用作诊断梅尼埃病和评估其诊断特征的工具。
该研究对53例确诊为单侧梅尼埃病的患者和一个正常组进行。计算了各组的均值及其95%置信区间,并绘制了相应的图表。使用独立样本t检验来检查正常组和梅尼埃病组之间SVV结果的差异。然后使用ROC曲线确定临界点并进行计算。
在研究了三种SVV情况(向病变侧倾斜)的临界点后,确定2.1度的临界点,其敏感性和特异性约为0.7,是区分梅尼埃病组和健康组的最佳情况。
最后,基于研究结果可以得出结论,SVV测试对梅尼埃病的诊断敏感性相对较低。因此,仅依靠其结果来识别梅尼埃病是不够的,建议在未来的研究中纳入ECochG和SVV测试之外的其他措施进行进一步调查。