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鼓室外电耳蜗图在梅尼埃病诊断中的临床应用价值

Clinical usefulness of extratympanic electrocochleography in the diagnosis of Ménière's disease.

作者信息

Chung Won-Ho, Cho Do-Yeon, Choi Jong-Yoon, Hong Sung Hwa

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.

出版信息

Otol Neurotol. 2004 Mar;25(2):144-9. doi: 10.1097/00129492-200403000-00011.

Abstract

OBJECTIVE

Electrocochleography has been introduced to aid the diagnosis of endolymphatic hydrops. The aim of this study was to evaluate the clinical effectiveness of extratympanic electrocochleography in the diagnosis of Ménière's disease.

STUDY DESIGN

The medical records of patients diagnosed as having Ménière's disease at the department of otolaryngology were reviewed retrospectively. Thirty-seven healthy ears were included to calculate the upper level of the 95th percentile range of the extratympanic electrocochleography variables.

SETTING

Tertiary referral university hospital.

PATIENTS

One hundred fifty-eight patients (97 women and 61 men) diagnosed as having Ménière's disease without previous treatments were included. A retrospective analysis of their medical records, electrocochleographic results, audiograms, and follow-up records was performed. The mean age was 48.6 years.

MAIN OUTCOME MEASURES

The upper level of the 95th percentile range of the extratympanic electrocochleography variables of normal subjects were calculated. Electrocochleography recording results were compared with the diagnostic scale and stage, presence of fluctuating hearing loss, and duration of symptoms.

RESULTS

The 95% upper limit for baseline summating potential and action potential ratio was 0.34. Sensitivity and specificity of electrocochleography in the diagnosis of Ménière's disease were 71% and 96%, respectively. The results statistically correlated with the Ménière's current diagnostic criteria and did not correlate with the stage of disease, presence of fluctuating hearing loss, or duration of symptoms.

CONCLUSION

Extratympanic electrocochleography may play an important role, especially in patients with less definite symptoms, but the diagnosis should also be anchored in the patient's clinical history, symptoms, and audiogram.

摘要

目的

耳蜗电图已被用于辅助诊断内淋巴积水。本研究旨在评估鼓室外耳蜗电图在梅尼埃病诊断中的临床有效性。

研究设计

回顾性分析在耳鼻喉科被诊断为梅尼埃病的患者的病历。纳入37只健康耳朵以计算鼓室外耳蜗电图变量第95百分位数范围的上限。

研究地点

三级转诊大学医院。

患者

纳入158例未经治疗的梅尼埃病患者(97例女性和61例男性)。对他们的病历、耳蜗电图结果、听力图和随访记录进行回顾性分析。平均年龄为48.6岁。

主要观察指标

计算正常受试者鼓室外耳蜗电图变量第95百分位数范围的上限。将耳蜗电图记录结果与诊断量表和分期、波动性听力损失的存在情况以及症状持续时间进行比较。

结果

基线总和电位与动作电位比值的95%上限为0.34。耳蜗电图对梅尼埃病诊断的敏感性和特异性分别为71%和96%。结果与梅尼埃病当前诊断标准具有统计学相关性,与疾病分期、波动性听力损失的存在情况或症状持续时间无关。

结论

鼓室外耳蜗电图可能发挥重要作用,尤其是对于症状不太明确的患者,但诊断也应基于患者的临床病史、症状和听力图。

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