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西尼罗河病毒:贝尔麻痹被忽视的病因?

West Nile Virus: A Neglected Cause of Bell's Palsy?

作者信息

Al-Hashimi Ibrahim, Okon Emmanuel

机构信息

Department of Internal Medicine, University of Texas (UT) at Tyler Health Science Center, UT Health East Texas, Tyler, USA.

Department of Infectious Diseases, Christus Trinity Clinic, Tyler, USA.

出版信息

Cureus. 2024 Jun 16;16(6):e62486. doi: 10.7759/cureus.62486. eCollection 2024 Jun.

DOI:10.7759/cureus.62486
PMID:39015861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11251707/
Abstract

The West Nile virus (WNV) is the leading cause of mosquito-borne disease in the United States. Bell's palsy (BP) is a clinical syndrome associated with viral infections, but an association with West Nile virus (WNV) is not well-described, with only two cases reported in the literature. We present a case of a 68-year-old woman presenting with fevers and encephalopathy. Cerebrospinal fluid was positive for WNV. Following improvement, she developed facial weakness and was diagnosed with BP secondary to the WNV infection. Identifying BP associated with WNV infection may have significant clinical implications, but further studies are needed to fully characterize a causative relationship.

摘要

西尼罗河病毒(WNV)是美国蚊媒疾病的主要病因。贝尔麻痹(BP)是一种与病毒感染相关的临床综合征,但与西尼罗河病毒(WNV)的关联尚未得到充分描述,文献中仅报道了两例。我们报告一例68岁女性,出现发热和脑病。脑脊液WNV检测呈阳性。病情好转后,她出现面部无力,被诊断为WNV感染继发的BP。识别与WNV感染相关的BP可能具有重要的临床意义,但需要进一步研究以充分阐明因果关系。

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本文引用的文献

1
Introduction to West Nile Virus.西尼罗河病毒简介。
Methods Mol Biol. 2023;2585:1-7. doi: 10.1007/978-1-0716-2760-0_1.
2
New-onset Bell's palsy after neuroinvasive West Nile virus.感染神经的西尼罗河病毒后出现新发贝尔氏麻痹。
BMJ Case Rep. 2022 Jul 14;15(7):e249770. doi: 10.1136/bcr-2022-249770.
3
Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis.新冠疫苗接种、SARS-CoV-2 感染与免疫介导的神经系统事件风险的关联:基于人群的队列和自身对照病例系列分析。
BMJ. 2022 Mar 16;376:e068373. doi: 10.1136/bmj-2021-068373.
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[Usutu virus: let's be vigilant].[乌苏图病毒:我们要保持警惕]
Virologie (Montrouge). 2018 Oct 1;22(5):233-236. doi: 10.1684/vir.2018.0749.
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New onset of Bell's palsy in a patient with West Nile Encephalitis.一名患有西尼罗河脑炎的患者新发贝尔麻痹。
Clin Case Rep. 2020 Jun 18;8(10):1895-1899. doi: 10.1002/ccr3.3009. eCollection 2020 Oct.
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The etiology of Bell's palsy: a review.贝尔面瘫的病因:综述
J Neurol. 2020 Jul;267(7):1896-1905. doi: 10.1007/s00415-019-09282-4. Epub 2019 Mar 28.
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Facial palsy associated with Epstein-Barr infection in an adult patient: case report.成年患者中与爱泼斯坦-巴尔病毒感染相关的面神经麻痹:病例报告
Intern Emerg Med. 2019 Apr;14(3):479-480. doi: 10.1007/s11739-019-02052-0. Epub 2019 Feb 20.
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The role of facial canal diameter in the pathogenesis and grade of Bell's palsy: a study by high resolution computed tomography.面神经管直径在贝尔面瘫发病机制及分级中的作用:一项高分辨率计算机断层扫描研究
Braz J Otorhinolaryngol. 2017 May-Jun;83(3):261-268. doi: 10.1016/j.bjorl.2016.03.016. Epub 2016 Apr 29.
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Differences in the diameter of facial nerve and facial canal in bell's palsy--a 3-dimensional temporal bone study.贝尔面瘫中面神经及面神经管直径差异——颞骨三维研究
Otol Neurotol. 2014 Mar;35(3):514-8. doi: 10.1097/MAO.0000000000000240.
10
The neurologist's dilemma: a comprehensive clinical review of Bell's palsy, with emphasis on current management trends.神经科医生的困境:贝尔麻痹的全面临床综述,重点关注当前的管理趋势。
Med Sci Monit. 2014 Jan 20;20:83-90. doi: 10.12659/MSM.889876.