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肝门部胆管癌内镜逆行胰胆管造影术后并发急性胆管炎伴菌血症:一例报告

Acute cholangitis with bacteremia after endoscopic retrograde cholangiopancreatography in hilar cholangiocarcinoma: A case report.

作者信息

Jo Ik Hyun, Ko Sung Woo

机构信息

Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 16471, South Korea.

Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, South Korea.

出版信息

World J Clin Cases. 2024 Jul 16;12(20):4377-4383. doi: 10.12998/wjcc.v12.i20.4377.

Abstract

BACKGROUND

is a Gram-negative opportunistic aerobe, usually causing nosocomial infections in immunocompromised patients with manifestations including bacteremia, pneumonia, and catheter-related infections. However, have not yet been reported to cause biliary system infections.

CASE SUMMARY

A 72-year-old woman presented to the outpatient department of our hospital with a chief complaint of jaundice. Computed tomography of her abdomen revealed the presence of a mass of approximately 2.4 cm in the hilar portion of the common hepatic duct, consistent with hilar cholangiocarcinoma. We performed endoscopic retrograde cholangiopancreatography (ERCP) to decompress the obstructed left and right intrahepatic ducts (IHDs) and placed 10 cm and 11 cm biliary stents in the left and right IHDs, respectively. However, the day after the procedure, the patient developed post-ERCP cholangitis as the length of the right IHD stent was insufficient for proper bile drainage. The blood culture of the patient tested positive for . Management measures included the replacement of the right IHD stent (11 cm) with a longer one (12 cm) and administering culture-directed antibiotic therapy, solving the cholangitis-related complications. After the cholangitis had resolved, the patient underwent surgery for hilar cholangiocarcinoma and survived for 912 d without recurrence.

CONCLUSION

-induced biliary system infections are extremely rare. Clinical awareness of physicians and endoscopists is required as this rare pathogen might cause infection after endoscopic procedures.

摘要

背景

[病原菌名称]是一种革兰氏阴性机会性需氧菌,通常在免疫功能低下的患者中引起医院感染,表现包括菌血症、肺炎和导管相关感染。然而,尚未有该菌引起胆道系统感染的报道。

病例摘要

一名72岁女性因黄疸为主诉前来我院门诊。腹部计算机断层扫描显示肝总管肝门部有一个约2.4 cm的肿块,符合肝门部胆管癌。我们进行了内镜逆行胰胆管造影(ERCP)以解除梗阻的左右肝内胆管(IHD),并分别在左右IHD放置了10 cm和11 cm的胆道支架。然而,术后第二天,由于右IHD支架长度不足以实现充分胆汁引流,患者发生了ERCP后胆管炎。患者的血培养检测到[病原菌名称]呈阳性。管理措施包括将右IHD支架(11 cm)更换为更长的(12 cm),并给予针对性培养的抗生素治疗,解决了胆管炎相关并发症。胆管炎消退后,患者接受了肝门部胆管癌手术,存活912天无复发。

结论

[病原菌名称]引起的胆道系统感染极为罕见。由于这种罕见病原体可能在内镜手术后引起感染,医生和内镜医师需要有临床意识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dd8/11235522/c94f8be70f91/WJCC-12-4377-g001.jpg

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