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抗肿瘤药物儿童用药安全事件根本原因分析。

Root cause analysis of safety incidents in antineoplastic use in children.

机构信息

Universidade Federal do Rio de Janeiro. Rio de Janeiro, Rio de Janeiro, Brazil.

Instituto Nacional de Câncer. Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Rev Bras Enferm. 2024 Jul 15;77Suppl 3(Suppl 3):e20230139. doi: 10.1590/0034-7167-2021-0139. eCollection 2024.

DOI:10.1590/0034-7167-2021-0139
PMID:39016429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11253835/
Abstract

OBJECTIVES

to identify and analyze the factors that contribute to safety incident occurrence in the processes of prescribing, preparing and dispensing antineoplastic medications in pediatric oncology patients.

METHODS

a quality improvement study focused on oncopediatric pharmaceutical care processes that identified and analyzed incidents between 2019-2020. A multidisciplinary group performed root cause analysis (RCA), identifying main contributing factors.

RESULTS

in 2019, seven incidents were recorded, 57% of which were prescription-related. In 2020, through active search, 34 incidents were identified, 65% relating to prescription, 29% to preparation and 6% to dispensing. The main contributing factors were interruptions, lack of electronic alert, work overload, training and staff shortages.

CONCLUSIONS

the results showed that adequate recording and application of RCA to identified incidents can provide improvements in the quality of pediatric oncology care, mapping contributing factors and enabling managers to develop an effective action plan to mitigate risks associated with the process.

摘要

目的

识别和分析导致儿科肿瘤患者在开具、准备和分发抗肿瘤药物过程中发生安全事件的因素。

方法

一项质量改进研究侧重于肿瘤儿科药物治疗过程,该研究在 2019-2020 年期间识别和分析了事件。一个多学科小组进行了根本原因分析(RCA),确定了主要的促成因素。

结果

2019 年记录了 7 起事件,其中 57%与处方有关。2020 年,通过主动搜索,确定了 34 起事件,其中 65%与处方有关,29%与准备有关,6%与分发有关。主要促成因素包括中断、缺乏电子警报、工作负荷过重、培训和人员短缺。

结论

结果表明,充分记录和应用 RCA 对已识别事件的分析可以提高儿科肿瘤护理质量,映射促成因素,并使管理人员能够制定有效的行动计划,以减轻与该过程相关的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/730c1d0d8abc/0034-7167-reben-77-s3-e20230139-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/05365b868e0f/0034-7167-reben-77-s3-e20230139-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/ce054a0a92f4/0034-7167-reben-77-s3-e20230139-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/adeaf388d1a0/0034-7167-reben-77-s3-e20230139-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/730c1d0d8abc/0034-7167-reben-77-s3-e20230139-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/05365b868e0f/0034-7167-reben-77-s3-e20230139-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/ce054a0a92f4/0034-7167-reben-77-s3-e20230139-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/adeaf388d1a0/0034-7167-reben-77-s3-e20230139-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a9b/11253835/730c1d0d8abc/0034-7167-reben-77-s3-e20230139-gf04.jpg

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Cancer. 2023 Apr 1;129(7):1064-1074. doi: 10.1002/cncr.34651. Epub 2023 Jan 27.
2
Building new standards to prevent harm from medication errors in children with cancer.制定新的标准以防止癌症患儿用药错误造成伤害。
Cancer. 2023 Apr 1;129(7):989-991. doi: 10.1002/cncr.34650. Epub 2023 Jan 27.
3
Medication errors in a children's inpatient antineoplastic chemotherapy facility.
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Bol Med Hosp Infant Mex. 2022;79(3):180-186. doi: 10.24875/BMHIM.21000175.
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The Healthcare Failure Mode and Effect Analysis as a tool to evaluate care protocols.医疗保健失效模式与影响分析作为评估护理方案的工具。
Rev Bras Enferm. 2022 Feb 2;75(3):e20210153. doi: 10.1590/0034-7167-2021-0153. eCollection 2022.
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Pharmacists' interventions on 2 years of drug monitoring in an oncology pediatric inpatient ward.药师在肿瘤科儿科住院病房进行为期两年的药物监测干预。
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