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撤回声明:甲基螺旋甾醇通过下调ERK1/2信号通路抑制肝星状细胞活化。

RETRACTION: Methyl Helicterate Inhibits Hepatic Stellate Cell Activation through Downregulating the ERK1/2 Signaling Pathway.

出版信息

J Cell Biochem. 2024 Oct;125(10):e30623. doi: 10.1002/jcb.30623. Epub 2024 Jul 17.

DOI:10.1002/jcb.30623
PMID:39016547
Abstract

Y. Wei, X. Zhang, S. Wen, S. Huang, Q. Huang, S. Lu, F. Bai, J. Nie, J. Wei, Z. Lu, and X. Lin. Methyl Helicterate Inhibits Hepatic Stellate Cell Activation Through Downregulating the ERK1/2 Signaling Pathway. Journal of Cellular Biochemistry 120, no. 9 (2019): 14936-14945, https://doi.org/10.1002/jcb.28756. The above article, published online on 22 April 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Multiple image elements in Figures 2A, 3B, and 4 were found to have been previously published by the same author group in a different scientific context. Furthermore, splicing affecting Figures 5B and 5C has been detected. The authors state that, due to inadequate data management, they were unable to verify whether Figures 2A, 3B, and 4 pertain to this study or to other works, and that Figure 5B and 5C were inappropriately employed. The article is retracted as the editors have lost confidence in the accuracy of the data presented and consider the conclusions of the article to be invalid. The authors agree with the decision to retract the article and would like to extend their sincere apologies for any inconvenience caused.

摘要

魏 Y、张 X、温 S、黄 S、黄 Q、卢 S、白 F、聂 J、魏 J、卢 Z 和林 X。甲基刺囊酸通过下调 ERK1/2 信号通路抑制肝星状细胞活化。《细胞生物化学杂志》120 卷,第 9 期(2019 年):14936 - 14945,https://doi.org/10.1002/jcb.28756。上述文章于 2019 年 4 月 22 日在 Wiley Online Library(wileyonlinelibrary.com)在线发表,已根据作者、期刊主编克里斯蒂安·贝尔以及 Wiley Periodicals LLC 的协议撤回。撤回是由于第三方对文章中呈现的数据提出了担忧。发现图 2A、3B 和 4 中的多个图像元素先前已由同一作者团队在不同的科学背景下发表。此外,还检测到影响图 5B 和 5C 的拼接问题。作者表示,由于数据管理不足,他们无法核实图 2A、3B 和 4 是否与本研究或其他作品相关,并且图 5B 和 5C 被不当使用。由于编辑们对所呈现数据的准确性失去信心,并认为文章的结论无效,因此撤回该文章。作者同意撤回文章的决定,并就由此造成的任何不便深表歉意。

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