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撤稿声明:丙泊酚诱导的miR-219-5p通过抑制GPC3介导的Wnt/β-连环蛋白信号激活来抑制肝细胞癌的生长和侵袭。

RETRACTION: Propofol-Induced miR-219-5p Inhibits Growth and Invasion of Hepatocellular Carcinoma Through Suppression of GPC3-Mediated Wnt/β-Catenin Signalling Activation.

出版信息

J Cell Biochem. 2024 Nov;125(11):e30652. doi: 10.1002/jcb.30652. Epub 2024 Oct 8.

Abstract

T. Gong, X. Ning, Z. Deng, M. Liu, B. Zhou, X. Chen, S. Huang, Y. Xu, Z. Chen, and R. Luo, "Propofol-Induced miR-219-5p Inhibits Growth and Invasion of Hepatocellular Carcinoma Through Suppression of GPC3-Mediated Wnt/β-Catenin Signalling Activation," Journal of Cellular Biochemistry 120, no. 10 (2019): 16934-16945, https://doi.org/10.1002/jcb.28952. The above article, published online on 19 May 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Specifically, multiple areas of overlap were detected within and across Figures 1D, 2E and 2F. The authors acknowledged that unintentional mistakes were made during figure compilation and collaborated on the investigation into the detected issues. Even though they provided the raw data underlying the study, verification of the material's accuracy proved challenging due to the time elapsed since publication. As full accuracy of the provided material could no longer be ascertained, the editors have decided to retract the article, as they consider the identified issues to undermine the reliability of the presented research. The authors agree with the decision of retraction acknowledging that the identified issues may impact the overall interpretation of the research findings.

摘要

龚涛、宁雪、邓泽、刘敏、周斌、陈霞、黄帅、徐阳、陈泽、罗锐,“丙泊酚诱导的miR - 219 - 5p通过抑制GPC3介导的Wnt/β-连环蛋白信号激活抑制肝癌细胞的生长和侵袭”,《细胞生物化学杂志》第120卷,第10期(2019年):16934 - 16945页,https://doi.org/10.1002/jcb.28952 。上述文章于2019年5月19日在线发表于威利在线图书馆(wileyonlinelibrary.com),已根据作者、期刊主编克里斯蒂安·贝尔以及威利期刊有限责任公司之间的协议撤回。撤回该文章是因为第三方对文章中呈现的数据提出了担忧。具体而言,在图1D、2E和2F内部及之间检测到多个重叠区域。作者承认在图表编制过程中出现了无意的错误,并就所检测到的问题展开了合作调查。尽管他们提供了该研究的原始数据,但由于自发表以来时间已经过去,对材料准确性的核实证明具有挑战性。由于无法再确定所提供材料的完全准确性,编辑们决定撤回该文章,因为他们认为所发现的问题损害了所呈现研究的可靠性。作者同意撤回决定,并承认所发现的问题可能会影响对研究结果的整体解读。

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