Garborg I, Eide T J
Acta Pathol Microbiol Immunol Scand A. 1985 Sep;93(5):205-8. doi: 10.1111/j.1699-0463.1985.tb03942.x.
When all transurethrally resected material of 53 subsequent patients was microscopically examined, primary adenocarcinoma of the prostate was found in 18 patients and benign disease in 35. Only 9 of the patients with histologically confirmed malignancy of the prostate were clinically diagnosed. The proportion of prostatic chips that contained malignant tissue ranged from 1-96%. A mathematical analysis evaluating the probability of including a carcinoma when different numbers of blocks were processes was performed. The analysis showed that when the patient has a clinically malignant diagnosis the probability of 100% is reached by the processing of one block. If the patient has a clinically benign diagnosis, however, the probability of 98% is first reached by the processing of 8 blocks, if such an amount of material is available.
对随后53例患者经尿道切除的所有组织进行显微镜检查，发现18例为前列腺原发性腺癌，35例为良性疾病。在组织学确诊为前列腺恶性肿瘤的患者中，只有9例得到临床诊断。含有恶性组织的前列腺组织碎片比例为1%-96%。对处理不同数量组织块时包含癌组织的概率进行了数学分析。分析表明，当患者临床诊断为恶性时，处理1个组织块达到100%的概率。然而，如果患者临床诊断为良性，在有足够材料的情况下，处理8个组织块时首次达到98%的概率。
