慢性疼痛患者从芬太尼贴片直接转为丁丙诺啡贴片。

Direct rotation from a fentanyl patch to a buprenorphine patch in a patient with chronic pain.

机构信息

Toronto Rehabilitation Institute, University Health Network, University of Toronto, Toronto, Canada. ORCID: https://orcid.org/0000-0001-7931-9134.

Toronto Rehabilitation Institute, University Health Network, University of Toronto, Toronto, Canada.

出版信息

J Opioid Manag. 2024 May-Jun;20(3):260-262. doi: 10.5055/jom.0865.

DOI:10.5055/jom.0865

PMID:39017618

Abstract

Transitioning a patient with chronic pain from a fentanyl patch to a buprenorphine patch has not been well described in the literature. Even after a patient removes their fentanyl patch, the residual fentanyl in the skin continues to be absorbed for hours. Due to the risk of precipitated withdrawal when initiating buprenorphine, this transition is a more challenging opioid rotation to plan safely. We report a case of a patient who had been using a fentanyl patch for over 10 years and was successfully rotated directly to a buprenorphine patch.

摘要

将患有慢性疼痛的患者从芬太尼贴片转换为丁丙诺啡贴片在文献中描述得并不充分。即使患者已经取下芬太尼贴片，皮肤中残留的芬太尼仍会在数小时内被吸收。由于开始使用丁丙诺啡时存在戒断症状加剧的风险，因此这种阿片类药物的转换更具挑战性，需要谨慎计划。我们报告了一例使用芬太尼贴片超过 10 年的患者，该患者成功地直接转换为丁丙诺啡贴片。