Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.
School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Eur Arch Otorhinolaryngol. 2024 Dec;281(12):6303-6316. doi: 10.1007/s00405-024-08847-y. Epub 2024 Jul 17.
Steroids given systemically, locally, or both are the mainstay of treatment for acute acoustic trauma (AAT). The overall recovery rate (full, partial, and none) is undetermined.
Original case series and systematic literature review.
Case series of a tertiary referral center and a systematic literature review.
Cases of AAT between 2012 and 2022 were retrospectively analyzed for demographics, acoustic trauma characteristics, treatment modality and delay and prognosis. This case series was added to the series identified by a systematic literature review. This review included "Medline" via "PubMed", "EMBASE", and "Google scholar". All series were pooled for meta-analysis defining prognosis following steroidal treatment for AAT patients.
The pooled analyses included 662 ears, out of which 250 underwent complete recovery of hearing (overall proportion = 0.2809, 95%confidence interval [CI] = 0.1611-0.4178). Any recovery was recorded for 477 ears (overall proportion = 0.7185, 95% CI = 0.5671-0.8493) and no recovery was documented for 185 ears (overall proportion = 0.2815, 95% CI = 0.1507-0.4329).
The rate of overall recovery for AAT is around 70%, and around 30% for full recovery when steroids are initiated within the first 2 weeks following the insult.
全身、局部或两者并用的类固醇是急性声创伤 (AAT) 治疗的主要方法。总体恢复率（完全、部分和无）尚不确定。
原始病例系列和系统文献回顾。
三级转诊中心的病例系列和系统文献回顾。
回顾性分析 2012 年至 2022 年间 AAT 的病例，以了解患者的人口统计学、声创伤特征、治疗方式和延迟以及预后。本病例系列与系统文献回顾中确定的系列相加。该综述包括“Medline”通过“PubMed”、“EMBASE”和“Google scholar”。所有系列均进行荟萃分析，定义 AAT 患者接受类固醇治疗后的预后。
汇总分析包括 662 只耳朵，其中 250 只耳朵听力完全恢复（总体比例为 0.2809，95%置信区间 [CI] = 0.1611-0.4178）。477 只耳朵记录到任何恢复（总体比例为 0.7185，95%CI = 0.5671-0.8493），185 只耳朵无恢复（总体比例为 0.2815，95%CI = 0.1507-0.4329）。
当在创伤后 2 周内开始使用类固醇时，AAT 的总体恢复率约为 70%，完全恢复率约为 30%。
