Department of Cardiology & Vascular Medicine, Dr Soetomo General Academic Hospital. Indonesia.
Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
J Pak Med Assoc. 2024 Jun;74(6 (Supple-6)):S13-S17. doi: 10.47391/JPMA.S6-ACSA-03.
To evaluate the factors associated with mortality among coronavirus disease-2019 patients with preexisting hypertension.
The retrospective, cross-sectional study was conducted from June 15 to July 7, 2021, after approval from Dr Soetomo General Province Hospital, Indonesia, and comprised data from the coronavirus disease-2019 registry in the East Java province of Indonesia from March 2020 to June 2021. Data was collected for adult patients infected by coronavirus disease-2019 with pre-existing hypertension Data was analysed using SPSS 23.
Of the 2,732 patients in the registry, 425(15.6%) with median age 56.5 years (interquartile range: 50-64 years) had pre-existing hypertension. Of them, 251(59.06%) were males, and 110(25.9%) had died while in hospital. Mortality was associated with older age; higher white blood cell counts at admission and lower platelet count (p<0.05). In addition, electrocardiogram parameters associated with mortality were faster heart rate and ST abnormality (p<0.05).
Older age, high white blood cell level, lower platelet count, faster heart rate, and ST abnormality at admission were found to be the predictors of mortality among hospitalised coronavirus disease-2019 patients with pre-existing hypertension.
评估 2019 冠状病毒病合并高血压患者死亡的相关因素。
本回顾性、横断面研究于 2021 年 6 月 15 日至 7 月 7 日在印度尼西亚苏托莫综合医院进行，纳入了 2020 年 3 月至 2021 年 6 月期间印度尼西亚东爪哇省 2019 冠状病毒病登记处的数据，这些数据来自患有高血压的成年 2019 冠状病毒病患者。数据采用 SPSS 23 进行分析。
在登记处的 2732 名患者中，425 名（15.6%）患者患有高血压，中位年龄为 56.5 岁（四分位间距：50-64 岁）。其中，251 名（59.06%）为男性，110 名（25.9%）在住院期间死亡。死亡率与年龄较大、入院时白细胞计数较高和血小板计数较低有关（p<0.05）。此外，与死亡率相关的心电图参数是心率较快和 ST 异常（p<0.05）。
年龄较大、白细胞计数较高、血小板计数较低、心率较快和入院时 ST 异常是预测合并高血压的 2019 冠状病毒病患者住院死亡率的指标。
