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临床发现和心电图预测了印度尼西亚东爪哇省有高血压既往史的 COVID-19 患者的死亡率:一项横断面研究。

Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia.

机构信息

Department of Cardiology & Vascular Medicine, Dr Soetomo General Academic Hospital. Indonesia.

Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.

出版信息

J Pak Med Assoc. 2024 Jun;74(6 (Supple-6)):S13-S17. doi: 10.47391/JPMA.S6-ACSA-03.

Abstract

OBJECTIVE

To evaluate the factors associated with mortality among coronavirus disease-2019 patients with preexisting hypertension.

METHODS

The retrospective, cross-sectional study was conducted from June 15 to July 7, 2021, after approval from Dr Soetomo General Province Hospital, Indonesia, and comprised data from the coronavirus disease-2019 registry in the East Java province of Indonesia from March 2020 to June 2021. Data was collected for adult patients infected by coronavirus disease-2019 with pre-existing hypertension Data was analysed using SPSS 23.

RESULTS

Of the 2,732 patients in the registry, 425(15.6%) with median age 56.5 years (interquartile range: 50-64 years) had pre-existing hypertension. Of them, 251(59.06%) were males, and 110(25.9%) had died while in hospital. Mortality was associated with older age; higher white blood cell counts at admission and lower platelet count (p<0.05). In addition, electrocardiogram parameters associated with mortality were faster heart rate and ST abnormality (p<0.05).

CONCLUSIONS

Older age, high white blood cell level, lower platelet count, faster heart rate, and ST abnormality at admission were found to be the predictors of mortality among hospitalised coronavirus disease-2019 patients with pre-existing hypertension.

摘要

目的

评估 2019 冠状病毒病合并高血压患者死亡的相关因素。

方法

本回顾性、横断面研究于 2021 年 6 月 15 日至 7 月 7 日在印度尼西亚苏托莫综合医院进行,纳入了 2020 年 3 月至 2021 年 6 月期间印度尼西亚东爪哇省 2019 冠状病毒病登记处的数据,这些数据来自患有高血压的成年 2019 冠状病毒病患者。数据采用 SPSS 23 进行分析。

结果

在登记处的 2732 名患者中,425 名(15.6%)患者患有高血压,中位年龄为 56.5 岁(四分位间距:50-64 岁)。其中,251 名(59.06%)为男性,110 名(25.9%)在住院期间死亡。死亡率与年龄较大、入院时白细胞计数较高和血小板计数较低有关(p<0.05)。此外,与死亡率相关的心电图参数是心率较快和 ST 异常(p<0.05)。

结论

年龄较大、白细胞计数较高、血小板计数较低、心率较快和入院时 ST 异常是预测合并高血压的 2019 冠状病毒病患者住院死亡率的指标。

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