Audiology and Speech-Language Pathology Program, University of Ottawa, Ontario, Canada.
Child Hearing Laboratory, CHEO Research Institute, Ottawa, Ontario, Canada.
Am J Audiol. 2024 Sep 3;33(3):1023-1040. doi: 10.1044/2024_AJA-23-00272. Epub 2024 Jul 17.
Magnetic resonance imaging (MRI), electric compound action potential (eCAP), and electric auditory brainstem response (eABR) are among the routine assessments performed before and/or after cochlear implantation. The objective of this review was to systematically summarize and critically appraise existing evidence of the prognostic value of eCAP, eABR, and MRI for predicting post-cochlear implant (CI) speech perception outcomes in children, with a particular focus on the lesion site.
The present systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 statement. Three electronic databases (ProQuest, PubMed, and Scopus) were searched with no restrictions on language, publication status, or year of publication. Studies on children identified with sensorineural hearing loss, auditory neuropathy spectrum disorder, cochlear nerve deficiency, or cochleovestibular nerve abnormalities reporting the relevance of eCAP, eABR, and/or MRI results to CI speech perception outcomes were included. The literature search yielded 1,887 publications. Methodological quality and strength of evidence were assessed by the Crowe Critical Appraisal Tool and the Grading of Recommendations Assessment, Development, and Evaluation tool, respectively.
Of the 25 included studies, the relevance of eCAP, eABR, and/or MRI findings to post-CI speech perception outcomes was reported in 10, 11, and 11 studies, respectively. The studies were strongly in support of the prognostic value of eABR and MRI for CI outcomes. However, the relevance of eCAP findings to speech perception outcomes was uncertain.
Despite the promising findings, caution is warranted in interpreting them due to the observational and retrospective design of the included studies, as well as the heterogeneity of the population and the limited control of confounding factors within these studies.
磁共振成像（MRI）、电复合动作电位（eCAP）和电听脑干反应（eABR）是在人工耳蜗植入前后常规进行的评估之一。本研究的目的是系统地总结和批判性评价现有关于 eCAP、eABR 和 MRI 对预测儿童人工耳蜗植入后（CI）言语感知结果的预后价值的证据，特别关注病变部位。
本系统评价按照 2020 年系统评价和荟萃分析的首选报告项目进行。无语言、出版状态或出版年份限制，在 ProQuest、PubMed 和 Scopus 三个电子数据库中进行了搜索。纳入的研究对象为患有感音神经性听力损失、听神经病谱系障碍、耳蜗神经缺陷或耳蜗前庭神经异常的儿童，报告了 eCAP、eABR 和/或 MRI 结果与 CI 言语感知结果的相关性。文献检索产生了 1887 篇出版物。采用 Crowe 批判性评估工具和推荐评估、制定和评估工具分别评估方法学质量和证据强度。
在 25 项纳入的研究中，有 10 项、11 项和 11 项研究分别报告了 eCAP、eABR 和/或 MRI 结果与 CI 后言语感知结果的相关性。这些研究强烈支持 eABR 和 MRI 对 CI 结果的预后价值。然而，eCAP 结果与言语感知结果的相关性尚不确定。
尽管有很有前景的发现，但由于纳入研究的观察性和回顾性设计，以及这些研究人群的异质性和对混杂因素的有限控制，在解释这些发现时需要谨慎。
