Department of Nanotechnology, Noorul Islam Center for Higher Education, Kumaracoil, Thuckalay, Tamil Nadu, India.
PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous), Affiliated to Bharathidasan University, Thanjavur, Tamil Nadu, India.
Luminescence. 2024 Jul;39(7):e4817. doi: 10.1002/bio.4817.
Alternate antibiotics developed through the involvement of nanomaterials are gaining interest due to their economical and lower toxicity concerns. A newly developed biopolymer-based polyvinylpyrrolidone/zinc oxide (PVP/ZnO) nanocomposite (NCs) was efficiently synthesized by an environment-friendly approach, utilizing onion and garlic peel extract as a bio-surfactant, zinc acetate as the source, PVP as the stabilizing agent, and sodium hydroxide as the precipitant. Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) investigations verified the crystalline properties of ZnO, PVP, and PVP/ZnO-based NCs. The structure of the biopolymer-linked ZnO particles interpolated inside the PVP array was seen to have a layered and flaky structure, as validated by field emission scanning electron microscopy (FE-SEM) analysis, which revealed its occurrence in the nanometer range. The XRD examination verified that the surface topographical image of PVP/ZnO NCs had an average thickness of 21 nm. The PVP/ZnO nanocrystals demonstrated exceptional photocatalytic efficacy, with a breakdown rate of 88% and almost 92% for the methylene blue dye. Therefore, the PVP/ZnO matrix exhibits superior antibacterial activity compared to other extracts, resulting in greater microbial suppression. The results above indicate that the ZnO-intercalated PVP array has a stronger reinforcing effect than other components. Hence, PVP/ZnO nanocrystals exhibit enormous potential as a favorable substance for environmental and biomedical intentions.
由于其经济性和较低的毒性问题，通过涉及纳米材料开发的替代抗生素引起了人们的兴趣。一种新开发的基于生物聚合物的聚乙烯吡咯烷酮/氧化锌（PVP/ZnO）纳米复合材料（NCs）通过一种环保的方法高效合成，利用洋葱和大蒜皮提取物作为生物表面活性剂，醋酸锌作为来源，PVP 作为稳定剂，氢氧化钠作为沉淀剂。傅里叶变换红外光谱（FT-IR）和 X 射线衍射（XRD）研究证实了 ZnO、PVP 和基于 PVP/ZnO 的 NCs 的结晶性质。通过场发射扫描电子显微镜（FE-SEM）分析验证了生物聚合物连接的 ZnO 颗粒在 PVP 阵列中的层状和片状结构，该分析表明其在纳米范围内存在。XRD 检查证实了 PVP/ZnO NCs 的表面形貌图像的平均厚度为 21nm。PVP/ZnO 纳米晶体表现出出色的光催化效率，对亚甲基蓝染料的分解率达到 88%，几乎达到 92%。因此，与其他提取物相比，PVP/ZnO 基体表现出更高的抗菌活性，从而实现更好的微生物抑制效果。上述结果表明，ZnO 插层的 PVP 阵列比其他成分具有更强的增强效果。因此，PVP/ZnO 纳米晶体具有作为环境和生物医学用途的有利物质的巨大潜力。
