Li Yijie, Zhang Wei, Wu Ye, Yin Li, Zhu Ce, Chen Yuqian, Cetin-Karayumak Suheyla, Cho Kang Ik K, Zekelman Leo R, Rushmore Jarrett, Rathi Yogesh, Makris Nikos, O'Donnell Lauren J, Zhang Fan
School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu, China.
School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, China.
Sci Data. 2024 Jul 17;11(1):787. doi: 10.1038/s41597-024-03624-2.
The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool in assessing white matter (WM) connectivity and brain tissue microstructure across different populations. However, a comprehensive investigation into WM fiber tracts between Eastern and Western populations is challenged due to the lack of a cross-population WM atlas and the large site-specific variability of dMRI data. This study presents a dMRI tractography atlas, namely the East-West WM Atlas, for concurrent WM mapping between Eastern and Western populations and creates a large, harmonized dMRI dataset (n=306) based on the Human Connectome Project and the Chinese Human Connectome Project. The curated WM atlas, as well as subject-specific data including the harmonized dMRI data, the whole brain tractography data, and parcellated WM fiber tracts and their diffusion measures, are publicly released. This resource is a valuable addition to facilitating the exploration of brain commonalities and differences across diverse cultural backgrounds.
对东西方人群大脑差异的研究为理解文化和基因对认知及心理健康的潜在影响提供了至关重要的见解。扩散磁共振成像（dMRI）纤维束成像技术是评估不同人群白质（WM）连接性和脑组织微观结构的重要工具。然而，由于缺乏跨人群的WM图谱以及dMRI数据存在较大的站点特异性差异，对东西方人群之间的WM纤维束进行全面研究面临挑战。本研究展示了一个dMRI纤维束成像图谱，即东西方WM图谱，用于同时对东西方人群进行WM映射，并基于人类连接组计划和中国人类连接组计划创建了一个大型的、经过协调的dMRI数据集（n = 306）。精心策划的WM图谱以及包括协调后的dMRI数据、全脑纤维束成像数据、分割后的WM纤维束及其扩散测量值在内的个体特异性数据已公开发布。这一资源对于促进探索不同文化背景下大脑的共性和差异而言是一项宝贵的补充。
