基于图谱的模板与特定个体的纤维束成像:解决争议
Atlas-based templates vs. subject-specific tractography: resolving the debate.
作者信息
Schilling Kurt G, Zhang Fan, Tournier J-Donald, Vergani Francesco, Sotiropoulos Stamatios N, Rokem Ariel, O'Donnell Lauren J
机构信息
Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
University of Electronic Science and Technology of China, Chengdu, China.
出版信息
Brain Struct Funct. 2025 Aug 26;230(7):141. doi: 10.1007/s00429-025-02974-w.
The first annual International Society of Tractography (IST) debate in Corsica in 2024 explored key challenges and controversies in tractography. This article examines the debate sparked by the provocative statement, "Tractography cannot give us anything we can't get from an atlas template." This debate contrasted two approaches: (1) white matter atlas templates, which provide standardized, population-based brain representations useful for studying brain structure and performing group comparisons, and (2) subject-specific tractography, which reconstructs individual brain connections using diffusion MRI, enabling in vivo "virtual dissection" of white matter pathways. We introduce key concepts, present arguments for and against this statement, and, as advocates of tractography, highlight its value while acknowledging the strengths of both approaches.
2024年在科西嘉岛举行的第一届年度国际纤维束成像学会(IST)辩论探讨了纤维束成像中的关键挑战和争议。本文审视了由“纤维束成像无法为我们提供任何从图谱模板中无法获得的东西”这一挑衅性言论引发的辩论。这场辩论对比了两种方法:(1)白质图谱模板,它提供了基于人群的标准化脑图谱,有助于研究脑结构和进行组间比较;(2)个体特异性纤维束成像,它利用扩散磁共振成像重建个体脑连接,实现白质通路的体内“虚拟解剖”。我们介绍关键概念,阐述支持和反对这一言论的论据,并且作为纤维束成像的倡导者,在承认两种方法优点的同时强调其价值。
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本文引用的文献
Imaging Neurosci (Camb). 2024-8-13
Hum Brain Mapp. 2022-10-1
Proc Natl Acad Sci U S A. 2022-4-5