Department of Radiology, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, China.
Department of Radiology, Shaoxing Hospital of Traditional Chinese Medicine, Shaoxing, China.
J Thorac Imaging. 2024 Nov 1;39(6):392-398. doi: 10.1097/RTI.0000000000000797. Epub 2024 Jul 18.
To investigate the imaging performance and parametric analysis of magnetic resonance imaging (MRI) immediately after microwave ablation (MWA) of lung malignancies.
We retrospectively analyzed the MRI performance immediately after MWA of 34 cases of lung malignancies. The ablation zone parameters of lung malignancies were measured, including the long diameter (L), short diameter (S), and safety margin of the ablation zone on plain computed tomography (CT), T1-weighted imaging (T1WI), and T2-weighted imaging (T2WI) after MWA. The study calculated the tumor volume (V 0 ), the ablation zone volume (V 1 ), and the ratio of V 0 to V 1 (V%). Statistical differences between the parameters were analyzed.
The ablation area of the lesion exhibited central low signal and peripheral high signal on T2WI, central high signal and peripheral equal or high signal on T1WI, and circumferential enhancement in the periphery. The safety margin measured on T2WI was greater than that measured on plain CT and T1WI. On plain CT, the L, S, and V 1 were smaller in the effective treatment group than in the ineffective treatment group ( P <0.05). On T1WI, the V% and safety margin were greater in the effective treatment group than in the ineffective treatment group ( P =0.009 and P =0.016, respectively).
MRI may be a new, valuable method to assess immediate efficacy after MWA for lung malignancies using the ablation zone parameters V% on T1WI and safety margin on T2WI.
探讨肺部恶性肿瘤微波消融（MWA）即刻后磁共振成像（MRI）的影像学表现和参数分析。
我们回顾性分析了 34 例肺部恶性肿瘤 MWA 即刻后 MRI 表现。测量肺部恶性肿瘤消融区参数，包括 MWA 后平扫 CT、T1 加权成像（T1WI）和 T2 加权成像（T2WI）上的消融区长径（L）、短径（S）和安全边界。计算肿瘤体积（V0）、消融区体积（V1）和 V0 与 V1 的比值（V%）。分析参数间的统计学差异。
病灶的消融区在 T2WI 上呈中央低信号、外周高信号，在 T1WI 上呈中央高信号、外周等或高信号，外周呈环状强化。T2WI 上测量的安全边界大于平扫 CT 和 T1WI 上测量的安全边界。平扫 CT 上，有效治疗组的 L、S 和 V1 均小于无效治疗组（P<0.05）。T1WI 上，有效治疗组的 V%和安全边界均大于无效治疗组（P=0.009 和 P=0.016）。
MRI 可能是一种新的、有价值的方法，可利用 T1WI 上的消融区参数 V%和 T2WI 上的安全边界评估肺部恶性肿瘤 MWA 后的即刻疗效。
