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No clear benefit of preventive cranial radiotherapy in childhood Philadelphia-positive acute lymphoblastic leukemia: a retrospective analysis of the EsPhALL2010 study.

作者信息

Conter Valentino, Valsecchi Maria Grazia, De Lorenzo Paola, Gandemer Virginie, Heyman Mats, Saha Vaskar, Diaz Paulina, Li Chi-Kong, Attarbaschi Andishe, Escherich Gabriele, Stary Jan, Schrappe Martin, Pieters Rob, Cario Gunnar, Biondi Andrea

机构信息

Pediatrics and Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza.

Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; School of Medicine and Surgery, University of Milano-Bicocca.

出版信息

Haematologica. 2024 Nov 1;109(11):3766-3770. doi: 10.3324/haematol.2024.285253.

DOI:10.3324/haematol.2024.285253
PMID:39021218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11532704/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e35/11532704/68bee4f9f023/1093766.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e35/11532704/68bee4f9f023/1093766.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e35/11532704/68bee4f9f023/1093766.fig1.jpg

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本文引用的文献

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Dasatinib with intensive chemotherapy in de novo paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (CA180-372/COG AALL1122): a single-arm, multicentre, phase 2 trial.达沙替尼联合强化化疗治疗初治费城染色体阳性儿童急性淋巴细胞白血病（CA180-372/COG AALL1122）：一项单臂、多中心、2 期临床试验。
Lancet Haematol. 2023 Jul;10(7):e510-e520. doi: 10.1016/S2352-3026(23)00088-1.
2
Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial.伊马替尼治疗儿童费城染色体阳性急性淋巴细胞白血病（EsPhALL2010）：一项前瞻性、多组、开放标签、单臂临床试验。
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3
Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor.EsPhALL2004研究治疗儿童费城染色体阳性急性淋巴细胞白血病的长期随访：诊断时高白细胞计数是最强的预后因素。
Haematologica. 2019 Jan;104(1):e13-e16. doi: 10.3324/haematol.2018.199422. Epub 2018 Sep 13.
4
Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.达沙替尼联合强化化疗治疗费城染色体阳性儿童、青少年和年轻成人急性淋巴细胞白血病：儿童肿瘤学组 AALL0622 试验结果。
J Clin Oncol. 2018 Aug 1;36(22):2306-2314. doi: 10.1200/JCO.2017.76.7228. Epub 2018 May 29.
5
Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy.当代疗法治疗儿童急性淋巴细胞白血病中颅放疗的影响。
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Lancet Oncol. 2012 Sep;13(9):936-45. doi: 10.1016/S1470-2045(12)70377-7. Epub 2012 Aug 14.
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J Hematol Oncol. 2011 Oct 13;4:42. doi: 10.1186/1756-8722-4-42.
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Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study.伊马替尼改善费城染色体阳性急性淋巴细胞白血病患者的早期无事件生存率：一项儿童肿瘤学组研究
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