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本文引用的文献

1
Cross-sectional study of COVID-19 infection in patients with rheumatic diseases in a sample of a Damascene population, Syria.叙利亚大马士革人群样本中风湿病患者新冠病毒感染的横断面研究。
Ann Med Surg (Lond). 2023 Mar 14;85(4):689-693. doi: 10.1097/MS9.0000000000000274. eCollection 2023 Apr.
2
Post-acute sequelae of COVID-19 (PASC): a meta-narrative review of pathophysiology, prevalence, and management.新冠病毒病急性后遗症(PASC):病理生理学、患病率及管理的元叙事综述
SN Compr Clin Med. 2022;4(1):90. doi: 10.1007/s42399-022-01167-4. Epub 2022 Apr 4.
3
Sicca symptoms in post-acute COVID-19 syndrome.急性 COVID-19 综合征后的干燥症状
Oral Dis. 2022 Nov;28 Suppl 2:2620-2621. doi: 10.1111/odi.14159. Epub 2022 Feb 23.
4
Post-COVID-19 syndrome in patients with primary Sjögren's syndrome after acute SARS-CoV-2 infection.原发性干燥综合征患者急性感染SARS-CoV-2后出现的新型冠状病毒肺炎后综合征
Clin Exp Rheumatol. 2021 Nov-Dec;39 Suppl 133(6):57-65. doi: 10.55563/clinexprheumatol/0anatx. Epub 2021 Nov 22.
5
Ocular findings among patients surviving COVID-19.COVID-19 幸存者的眼部表现。
Sci Rep. 2021 May 26;11(1):11085. doi: 10.1038/s41598-021-90482-2.
6
Post-acute COVID-19 syndrome.新冠病毒感染后长期综合征。
Nat Med. 2021 Apr;27(4):601-615. doi: 10.1038/s41591-021-01283-z. Epub 2021 Mar 22.
7
Prevalence of dry mouth in COVID-19 patients with and without Sicca syndrome in a large hospital center.在一家大型医院中心,患有和未患有干燥综合征的新冠肺炎患者中口干症的患病率。
Ir J Med Sci. 2021 Nov;190(4):1639-1641. doi: 10.1007/s11845-020-02480-4. Epub 2021 Jan 12.
8
Oral Manifestations in Patients with COVID-19: A Living Systematic Review.《COVID-19 患者的口腔表现:一项实时系统综述》。
J Dent Res. 2021 Feb;100(2):141-154. doi: 10.1177/0022034520957289. Epub 2020 Sep 11.
9
Autoantibodies related to systemic autoimmune rheumatic diseases in severely ill patients with COVID-19.新冠肺炎重症患者中与系统性自身免疫性风湿疾病相关的自身抗体
Ann Rheum Dis. 2020 Dec;79(12):1661-1663. doi: 10.1136/annrheumdis-2020-218009. Epub 2020 Jun 24.
10
Brazilian oral medicine and oral pathology: We are here during the COVID-19 pandemic.巴西口腔医学与口腔病理学:我们正处于新冠疫情期间。
Oral Dis. 2021 Apr;27 Suppl 3(Suppl 3):757-759. doi: 10.1111/odi.13440. Epub 2020 Jun 18.

干燥综合征作为新型冠状病毒肺炎感染的并发症:一例病例报告。

Sicca syndrome as complication of COVID-19 infection: A case report.

作者信息

Tarcha Raghad, Khalayli Naram, Kudsi Maysoun

机构信息

Department of Rheumatology, Faculty of Medicine Damascus University Damascus Syria.

Department of Psychiatry, Faculty of Medicine Damascus University Damascus Syria.

出版信息

Clin Case Rep. 2024 Jul 16;12(7):e9177. doi: 10.1002/ccr3.9177. eCollection 2024 Jul.

DOI:10.1002/ccr3.9177
PMID:39021490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11252430/
Abstract

Several reports of suspected oral and ocular manifestations of coronavirus disease 2019 (COVID-19) has prompted investigations into ocular signs, symptoms, and transmission (5).11.2% of patients with COV19 infection had ocular symptoms, including ocular pain, conjunctivitis, dry eye, and floaters, meanwhile, many studies had documented oral symptoms such as dry mouth and dysgeusia in these patients. Our case reported a 39-year-old male, presented with symptoms of dry mouth and dry eye lasting more than 3 months. The patient had recovered from (PCR-confirmed) COVID-19 which lasted 10 days, 4 months ago. The physical examination was normal. Ocular findings include conjunctival hyperemia and superficial punctate keratitis. The anti-nuclear antibody (ANA) was weekly positive at 1/80. Schirmer test considered positive. He continued on 200 mg/day of hydroxychloroquine, along with tear drops until now with remission. Sicca symptoms may be a sequel of COVID-19 infection, and physicians should be aware of this sequel. The sequela of this infection is not understood, with limited data in the literature. Future prospective cohort studies are needed to reveal the impact of these features on oral health.

摘要

几份关于2019冠状病毒病(COVID-19)疑似口腔和眼部表现的报告促使人们对眼部体征、症状及传播情况展开调查。11.2%的COVID-19感染患者有眼部症状,包括眼痛、结膜炎、干眼和飞蚊症,同时,许多研究记录了这些患者的口腔症状,如口干和味觉障碍。我们的病例报告了一名39岁男性,出现口干和干眼症状持续超过3个月。该患者4个月前从持续10天的(PCR确诊)COVID-19中康复。体格检查正常。眼部检查结果包括结膜充血和浅层点状角膜炎。抗核抗体(ANA)呈弱阳性,滴度为1/80。泪液分泌试验结果为阳性。他持续服用每日200毫克羟氯喹,并使用眼药水,直至症状缓解。干燥症状可能是COVID-19感染的后遗症,医生应了解这一后遗症。这种感染的后遗症尚不清楚,文献中的数据有限。未来需要进行前瞻性队列研究,以揭示这些特征对口腔健康的影响。