School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Department of Dermatology, China-Japan Friendship Hospital, Beijing, China.
Front Immunol. 2024 Jul 3;15:1347311. doi: 10.3389/fimmu.2024.1347311. eCollection 2024.
Corona virus disease 2019(COVID-19) is one of the most serious respiratory pandemic diseases threatening human health for centuries. Alopecia areata (AA) is a sudden patchy hair loss, an autoimmune disease, which seriously affects the image and mental health of patients. Evidence shows that the risk of autoimmune diseases significantly increases after COVID-19, and is positively correlated with the severity, with a significant increase in the risk of alopecia in those over 40 years old. The relationship between COVID-19 and AA has become a hot topic of current research. Strengthening the research on the correlation between COVID-19 and AA can help to identify and protect susceptible populations at an early stage. This article reviews the research progress on the epidemiological background of COVID-19 and AA, the situation and possible mechanisms of AA induced by COVID-19 or COVID-19 vaccination, and potential treatment methods.
新型冠状病毒肺炎（COVID-19）是威胁人类健康长达几个世纪之久的最严重呼吸道传染病之一。斑秃（AA）是一种突发性斑片状脱发，是一种自身免疫性疾病，严重影响患者的形象和心理健康。有证据表明，COVID-19 后自身免疫性疾病的风险显著增加，并且与严重程度呈正相关，40 岁以上人群发生脱发的风险显著增加。COVID-19 与 AA 之间的关系已成为当前研究的热点。加强 COVID-19 与 AA 之间相关性的研究有助于早期识别和保护易感人群。本文综述了 COVID-19 和 AA 的流行病学背景、COVID-19 或 COVID-19 疫苗诱导 AA 的情况和可能的机制以及潜在的治疗方法的研究进展。
