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病毒诱导的泛发性快速进展性脱发:一例报告及文献综述

Viral-Induced Rapidly Progressive Alopecia Universalis: A Case Report and Literature Review.

作者信息

Alotaibi Manar A, Altaymani Afrah, Al-Omair Abdullah, Alghamdi Waleed

机构信息

Dermatology, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, SAU.

Dermatology, College of Medicine, Jouf University, Sakaka, SAU.

出版信息

Cureus. 2023 Apr 10;15(4):e37406. doi: 10.7759/cureus.37406. eCollection 2023 Apr.

DOI:10.7759/cureus.37406
PMID:37181982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10171925/
Abstract

Alopecia areata is a common autoimmune condition that causes a non-scarring form of hair loss. It is associated with several viruses and diseases. One of the viruses that have been linked to alopecia areata is the coronavirus disease of 2019 (COVID-19). It was found to cause the onset, aggravation, or recurrence of alopecia areata in previously infected patients. We report the case of a 20-year-old woman who was medically free and presented with the severe and progressive onset of alopecia areata after one month of contracting COVID-19. This study aimed to explore the literature on COVID-19-associated severe onset alopecia areata in terms of timeline and clinical presentation.

摘要

斑秃是一种常见的自身免疫性疾病,可导致非瘢痕性脱发。它与多种病毒和疾病有关。与斑秃相关的病毒之一是2019冠状病毒病(COVID-19)。研究发现,它可导致既往感染患者出现斑秃、病情加重或复发。我们报告了一例20岁女性病例,该患者身体健康,在感染COVID-19一个月后出现严重且进行性加重的斑秃。本研究旨在从时间线和临床表现方面探讨与COVID-19相关的严重斑秃的文献。

相似文献

1
Viral-Induced Rapidly Progressive Alopecia Universalis: A Case Report and Literature Review.病毒诱导的泛发性快速进展性脱发:一例报告及文献综述
Cureus. 2023 Apr 10;15(4):e37406. doi: 10.7759/cureus.37406. eCollection 2023 Apr.
2
Hydroxychloroquine for granuloma annulare: A case report on secondary hair growth in alopecia universalis.羟氯喹治疗环状肉芽肿:泛发性斑秃继发毛发生长的病例报告
SAGE Open Med Case Rep. 2023 Jan 28;11:2050313X231152066. doi: 10.1177/2050313X231152066. eCollection 2023.
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Alopecia areata after COVID-19 vaccination.新冠疫苗接种后出现斑秃。
Clin Exp Vaccine Res. 2022 Jan;11(1):129-132. doi: 10.7774/cevr.2022.11.1.129. Epub 2022 Jan 31.
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Alopecia Areata Universalis Precipitated by SARS-CoV-2 Vaccine: A Case Report and Narrative Review.新冠病毒疫苗引发的全秃:一例报告及文献综述
Cureus. 2022 Aug 12;14(8):e27953. doi: 10.7759/cureus.27953. eCollection 2022 Aug.
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Alopecia areata: A multifactorial autoimmune condition.斑秃:一种多因素自身免疫性疾病。
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Systemic Lupus Erythematosus Presenting as Alopecia Areata.表现为斑秃的系统性红斑狼疮
Cureus. 2020 Jun 20;12(6):e8724. doi: 10.7759/cureus.8724.

引用本文的文献

1
Epidermal γδ T cells, CD8 T cells and macrophages are increased in number in alopecia areata and express BST2 as part of an interferon-driven antiviral gene signature.斑秃患者的表皮γδ T细胞、CD8 T细胞和巨噬细胞数量增加,并表达BST2,作为干扰素驱动的抗病毒基因特征的一部分。
bioRxiv. 2025 Jun 28:2025.06.26.661822. doi: 10.1101/2025.06.26.661822.
2
The correlation between corona virus disease 2019 and alopecia areata: a literature review.新型冠状病毒病 2019 与斑秃的相关性:文献综述。
Front Immunol. 2024 Jul 3;15:1347311. doi: 10.3389/fimmu.2024.1347311. eCollection 2024.

本文引用的文献

1
Spontaneous complete resolution of alopecia totalis post SARS-CoV-2 infection.新型冠状病毒感染后全秃自发完全缓解
JAAD Case Rep. 2022 Sep;27:106-109. doi: 10.1016/j.jdcr.2022.07.027. Epub 2022 Aug 3.
2
Not just thinning: A case of alopecia universalis after mild COVID-19.不仅仅是头发稀疏:一例轻症新冠病毒感染后的全秃病例。
JAAD Case Rep. 2022 Jul;25:1-3. doi: 10.1016/j.jdcr.2022.04.024. Epub 2022 May 7.
3
Association between alopecia areata and COVID-19: A systematic review.斑秃与2019冠状病毒病之间的关联:一项系统评价。
JAAD Int. 2022 Jun;7:57-61. doi: 10.1016/j.jdin.2022.02.002. Epub 2022 Feb 10.
4
New onset of alopecia areata in a patient with SARS-CoV-2 infection: Possible pathogenetic correlations?一名感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的患者出现斑秃:可能的发病机制关联?
J Cosmet Dermatol. 2021 Jul;20(7):2004-2005. doi: 10.1111/jocd.14080. Epub 2021 Mar 25.
5
Rapidly progressive alopecia areata totalis in a COVID-19 patient, unresponsive to tofacitinib.一名新冠病毒肺炎患者出现快速进展的全秃性斑秃,对托法替布无反应。
J Eur Acad Dermatol Venereol. 2021 Jul;35(7):e411-e412. doi: 10.1111/jdv.17170. Epub 2021 Mar 20.
6
COVID-19: association with rapidly progressive forms of alopecia areata.新型冠状病毒肺炎:与斑秃的快速进展形式相关。
Int J Dermatol. 2021 Jan;60(1):127. doi: 10.1111/ijd.15317. Epub 2020 Nov 23.
7
The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata.斑秃专家共识(ACE)研究第二部分:关于斑秃诊断和实验室评估的国际专家意见结果
J Am Acad Dermatol. 2021 Jun;84(6):1594-1601. doi: 10.1016/j.jaad.2020.09.028. Epub 2020 Sep 12.
8
Understanding the significance of cytokines and chemokines in the pathogenesis of alopecia areata.了解细胞因子和趋化因子在斑秃发病机制中的意义。
Exp Dermatol. 2020 Aug;29(8):726-732. doi: 10.1111/exd.14129. Epub 2020 Jul 3.
9
Alopecia areata: a review of disease pathogenesis.斑秃:疾病发病机制的综述。
Br J Dermatol. 2018 Nov;179(5):1033-1048. doi: 10.1111/bjd.16808. Epub 2018 Sep 9.
10
Evaluation of the Relationship between Alopecia Areata and Viral Antigen Exposure.评估斑秃与病毒抗原暴露的关系。
Am J Clin Dermatol. 2018 Feb;19(1):119-126. doi: 10.1007/s40257-017-0312-y.