Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor St Luke's Hospital, Baylor College of Medicine, Houston, Texas.
Division of Cardiovascular Surgery, The Texas Heart Institute, Houston, Texas.
Tex Heart Inst J. 2024 Jul 19;51(2). doi: 10.14503/THIJ-23-8167.
Minimally invasive mitral valve surgery (mini-MVS) is typically reserved for patients who have not undergone open cardiac surgery. In the reoperative setting, using intrapericardial dissection for crossclamping the aorta through a minimally invasive approach can be difficult and, at times, risky. Cold fibrillatory cardiac arrest (CFCA) with systemic cardiopulmonary bypass without cross-clamping is a well-described technique; however, data about its safety for patients who undergo reoperative mini-MVS are limited.
Data for 34 patients who underwent reoperative mini-MVS with CFCA from March 2017 to March 2022 were reviewed retrospectively. A mini right thoracotomy (n = 30) or robotic (n = 4) approach was used. Systemic hypothermia was induced to a target temperature of 25 °C.
Patient mean (SD) age was 64.5 (9.6) years, and 15 of 34 (44.1%) patients were women. Of those 34 patients, 23 (67.6%) had severe regurgitation, and 11 (32.4%) had severe stenosis. Before mini-MVS, 28 patients had undergone valve surgery, and 8 had undergone coronary artery bypass graft surgery. The mitral valve was repaired in 5 of 34 (14.7%) and replaced in 29 of 34 (85.3%) patients. No difference was observed in preoperative and postoperative left ventricular function (P = .82). In 1 patient, kidney failure developed that necessitated dialysis. No postoperative stroke or mortality at 30 days occurred.
Mini-MVS with CFCA is well tolerated in patients with prior cardiac surgery. Myocardial function was not impaired, nor was the risk of stroke increased in this cohort, indicating that CFCA is a safe alternative in this high-risk population.
微创二尖瓣手术(mini-MVS)通常仅适用于未接受过开胸心脏手术的患者。在再次手术中,通过微创途径在心包内进行主动脉交叉钳夹可能较为困难,且有时存在风险。非交叉钳夹常温体外循环下的冷颤停搏(CFCA)是一种描述详细的技术;然而,关于其用于再次行 mini-MVS 手术患者的安全性的数据有限。
回顾性分析 2017 年 3 月至 2022 年 3 月期间 34 例行再次 mini-MVS 联合 CFCA 的患者数据。采用微创右开胸(n=30)或机器人(n=4)方法。诱导全身低温至目标温度 25°C。
患者平均(SD)年龄为 64.5(9.6)岁,34 例患者中有 15 例(44.1%)为女性。这 34 例患者中,23 例(67.6%)存在严重反流,11 例(32.4%)存在严重狭窄。在 mini-MVS 之前,28 例患者已行瓣膜手术,8 例患者已行冠状动脉旁路移植术。34 例患者中,5 例(14.7%)行二尖瓣修复,29 例(85.3%)行二尖瓣置换。术前和术后左心室功能无差异(P=0.82)。1 例患者出现肾衰竭,需要透析。30 天内无术后卒中和死亡发生。
在既往有心脏手术的患者中,CFCA 联合 mini-MVS 可耐受良好。该队列中心肌功能未受损,卒中风险也未增加,表明 CFCA 是该高危人群的一种安全替代方法。