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孟加拉国住院儿童的肠致病性大肠杆菌腹泻

Enteropathogenic Escherichia coli diarrhea in hospitalized children in Bangladesh.

作者信息

Moyenuddin M, Rahman K M

出版信息

J Clin Microbiol. 1985 Nov;22(5):838-40. doi: 10.1128/jcm.22.5.838-840.1985.

Abstract

The role of enteropathogenic Escherichia coli (EPEC) was evaluated in a group of children with endemic diarrhea admitted to Dhaka Shishu Hospital in Dacca, Bangladesh. EPEC was detected in fecal samples of 23% of 104 cases and 8% of 74 concurrent control children. The most commonly isolated EPEC strains were serogroups O20a, O20c:K61; O20a, O20b:K84; O26:K60; and O18a, O18c:K77. Except for O26:K60, these groups had not been reported from Bangladesh. On testing for enterotoxin production, only two strains (serogroups O26:K60, O18a, and O18c:K77) were enterotoxigenic. None was enteroinvasive as tested in the guinea pig conjunctivitis model. Our study supports the concept that EPEC may be an important cause of endemic diarrhea in Bangladesh.

摘要

在孟加拉国达卡的达卡儿童医院收治的一组地方性腹泻儿童中,对肠致病性大肠杆菌(EPEC)的作用进行了评估。在104例病例的粪便样本中,23%检测到EPEC,74名同期对照儿童中有8%检测到EPEC。最常分离出的EPEC菌株血清群为O20a、O20c:K61;O20a、O20b:K84;O26:K60;以及O18a、O18c:K77。除O26:K60外,孟加拉国尚未报告过这些菌群。在检测产肠毒素情况时,只有两株菌株(血清群O26:K60、O18a和O18c:K77)产肠毒素。在豚鼠结膜炎模型中检测,无一株具有肠侵袭性。我们的研究支持EPEC可能是孟加拉国地方性腹泻重要病因这一观点。

相似文献

2
Diarrhoeagenic Escherichia coli in hospitalized children in Dhaka.
Bangladesh Med Res Counc Bull. 1985 Jun;11(1):20-7.

本文引用的文献

7
The role of enteropathogenic E. coli in infantile diarrhoea. Aspects on bacteriology, epidemiology and therapy.
Scand J Infect Dis Suppl. 1983;37:1-51. doi: 10.3109/inf.1982.14.suppl-37.01.

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