Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Ningxia, China.
Department of Cardiovascular Medicine, General Hospital of Ningxia Medical University, Ningxia, China.
Medicine (Baltimore). 2024 Jul 19;103(29):e38844. doi: 10.1097/MD.0000000000038844.
The aim of this study is to assess alterations in heart function and structure in patients diagnosed with non-ST segment elevation acute myocardial infarction (NSTEAMI), unstable angina (UA), and stable angina (SA) 1 year after undergoing off-pump coronary artery bypass grafting (OPCABG) performed without extracorporeal circulation. A total of 182 patients who underwent OPCABG were included and classified into 3 groups based on their preoperative diagnosis: the NSTEAMI group (n = 68), the UA group (n = 64), and the SA group (n = 50). Cardiac ultrasonography data were collected for all groups both preoperatively and 1 year postoperatively. Clinical data were subjected to statistical analysis. In the NSTEAMI group, postoperative observations revealed increases in left ventricular stroke volume and left ventricular end-systolic diameter, along with reductions in left ventricular end-diastolic volume (LVEDV) and left ventricular end-diastolic diameter (LVEDD) 1-year post-surgery. The UA group demonstrated decreases in LVEDV and LVEDD 1-year post-surgery. Similarly, the SA group exhibited an increase in left ventricular ejection fraction (LVEF) and reductions in LVEDV and LVEDD 1-year post-surgery. Comparative analysis of cardiac ultrasonography data revealed that the NSTEAMI group displayed significantly lower left ventricular stroke volume and notably higher left ventricular end-systolic diameter and volume compared to the UA and SA groups 1-year post-surgery. Furthermore, the SA group exhibited significantly elevated LVEF compared to the UA and NSTEAMI groups 1-year post-surgery. Cardiac ultrasonography findings indicate that all 3 groups exhibited improvements in cardiac function and left ventricular structure 1-year post-surgery. However, the NSTEAMI group demonstrated more substantial improvements in comparison to the UA and SA groups.
本研究旨在评估非 ST 段抬高急性心肌梗死（NSTEAMI）、不稳定型心绞痛（UA）和稳定型心绞痛（SA）患者在接受非体外循环下冠状动脉旁路移植术（OPCABG）治疗 1 年后心脏功能和结构的变化。共纳入 182 例行 OPCABG 的患者，根据术前诊断分为 3 组：NSTEAMI 组（n=68）、UA 组（n=64）和 SA 组（n=50）。所有组均在术前和术后 1 年采集心脏超声数据。对临床数据进行统计学分析。NSTEAMI 组术后观察到左心室每搏量和左心室收缩末期直径增加，左心室舒张末期容积（LVEDV）和左心室舒张末期直径（LVEDD）减少。UA 组术后 1 年 LVEDV 和 LVEDD 减少。同样，SA 组术后左心室射血分数（LVEF）增加，LVEDV 和 LVEDD 减少。心脏超声数据比较分析显示，NSTEAMI 组术后 1 年左心室每搏量明显低于 UA 和 SA 组，左心室收缩末期直径和容积明显高于 UA 和 SA 组。此外，SA 组术后 1 年 LVEF 明显高于 UA 和 NSTEAMI 组。心脏超声检查结果表明，所有 3 组术后 1 年均有心脏功能和左心室结构改善，但 NSTEAMI 组改善程度明显优于 UA 和 SA 组。
