Qin Qiuyuan, Temkin-Greener Helena, Veazie Peter, Makineni Rajesh, Cai Shubing
Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
J Appl Gerontol. 2025 Jan;44(1):11-17. doi: 10.1177/07334648241264908. Epub 2024 Jul 20.
Older adults with Alzheimer's disease and related dementias (ADRD) had a high risk of COVID-19-related mortality. Racial and ethnic minorities were disproportionally impacted by the pandemic. The variations in disparities, including racial and ethnic disparities and disparities across communities, in COVID-19-related mortality across the different stages of the COVID-19 pandemic among the ADRD population are unknown. This observational study estimated linear probability models for community-dwelling older adults with ADRD who were diagnosed with COVID-19 in 2020 and 2021 using multiple national data (e.g., Medicare data), accounting for individual and community characteristics. Disparities in 30-day mortality were compared between 2020 and 2021. The socioeconomic disparity in COVID-19-related mortality across communities became insignificant during the later stage of the pandemic, ethnic differences in COVID-19-related mortality decreased but persisted, and racial disparity remained largely unchanged. The study provides insights into interventions to mitigate lingering disparities in health outcomes among the vulnerable population.
患有阿尔茨海默病及相关痴呆症(ADRD)的老年人面临与新冠病毒疾病(COVID-19)相关的高死亡风险。少数族裔受到这场大流行病的影响尤为严重。在ADRD人群中,COVID-19大流行不同阶段与COVID-19相关的死亡率差异,包括种族和族裔差异以及不同社区之间的差异,目前尚不清楚。这项观察性研究使用多个国家数据(如医疗保险数据),针对2020年和2021年被诊断患有COVID-19的社区居住ADRD老年人估计了线性概率模型,同时考虑了个体和社区特征。比较了2020年和2021年30天死亡率的差异。在大流行后期,不同社区间与COVID-19相关的死亡率的社会经济差异变得不显著,与COVID-19相关的死亡率的种族差异有所下降但仍然存在,而种族差异基本保持不变。该研究为减轻弱势群体健康结果方面持续存在的差异的干预措施提供了见解。