Kessler M J, Howard C F, London W T
J Med Primatol. 1985;14(5):237-44.
Gestational diabetes mellitus was diagnosed in an aged (21-year-old) pregnant rhesus monkey (Macaca mulatta); she was hyperglycemic and had minimal glucose clearance in an intravenous glucose tolerance test (iv-GTT). An overweight (840 g) dead full-term fetus was delivered by cesarean section. A second iv-GTT conducted 3 months later revealed impaired glucose tolerance. While pregnant, the monkey was hyperinsulinemic and showed minimal secretory response to the glucose load. When tested postpartum, the fasting insulin was only slightly elevated, but the insulin response to glucose was still lacking.
一只21岁的老年怀孕恒河猴（猕猴）被诊断出患有妊娠期糖尿病；在静脉葡萄糖耐量试验（iv-GTT）中，它血糖过高且葡萄糖清除率极低。通过剖宫产分娩出一个超重（840克）的足月死胎。3个月后进行的第二次iv-GTT显示葡萄糖耐量受损。怀孕时，这只猴子胰岛素分泌过多，对葡萄糖负荷的分泌反应极小。产后检测时，空腹胰岛素仅略有升高，但对葡萄糖的胰岛素反应仍然缺乏。
