健康成年人中 SpotChecks 对比敏感度测试的评估。

Evaluation of the SpotChecks contrast sensitivity test in healthy adults.

机构信息

College of Optometry, University of Houston, Houston, Texas, USA.

Department of Mathematics, University of Houston, Houston, Texas, USA.

出版信息

Ophthalmic Physiol Opt. 2024 Sep;44(6):1072-1083. doi: 10.1111/opo.13349. Epub 2024 Jun 21.

DOI:10.1111/opo.13349

PMID:39031645

Abstract

PURPOSE

SpotChecks is a new contrast sensitivity (CS) test designed for self-monitoring of vision. This study assessed the test-retest repeatability of take-home SpotChecks, in-office SpotChecks and near Pelli-Robson charts in healthy adults.

METHODS

One eye of 61 healthy adults with near visual acuity (VA) of 6/9 or better (age range 22-84, mean 49 [18] years) was tested during two office visits (mean 10 [8] days apart). Each visit included high-contrast VA, then 12 randomly ordered CS tests (6 different SpotChecks and 6 different Pelli-Robson) under the same lighting (luminance 110 cd/m), all at near in the same eye with habitual correction. The same eye was self-tested with take-home SpotChecks once a day on 6 days between the office visits. SpotChecks was scored by the logCS at the highest line with ≥2 errors. Pelli-Robson was scored by [0.05 × number of letters read correctly - 0.15]. Repeatability of logCS was defined as 1.96 S, S representing within-subject standard deviation. Comparison for repeatability was performed with Bootstrap hypothesis test.

RESULTS

SpotChecks and Pelli-Robson showed similar intra-session or inter-visit repeatability (p = 0.14-0.81). Inter-day repeatability for take-home SpotChecks was 0.18 logCS, the same as that from the first measurements of two office visits with SpotChecks or Pelli-Robson. Inter-visit repeatability improved to 0.15 by using the average of two repeated measurements for SpotChecks (p = 0.02) or three repeated measurements for Pelli-Robson (p = 0.04). Age showed a small effect on logCS (-0.015/decade, p = 0.02) for both SpotChecks and Pelli-Robson. Mean logCS was 0.05 lower in those ≥50 years (SpotChecks 1.84 [0.10] and Pelli-Robson 1.77 [0.10]) compared with those <50 years of age (SpotChecks 1.89 [0.07] and Pelli-Robson 1.83 [0.07]).

CONCLUSIONS

SpotChecks showed good repeatability with take-home and in-office testing in healthy adults, making it a promising tool for monitoring disease progression at home.

摘要

目的

SpotChecks 是一种新的对比敏感度（CS）测试，专为视力自我监测而设计。本研究评估了健康成年人在家中使用 SpotChecks、在诊所使用 SpotChecks 和近视力 Pelli-Robson 图表的测试-再测试重复性。

方法

61 名年龄在 22-84 岁之间（平均 49[18]岁）、近视力（VA）为 6/9 或更好的健康成年人的一只眼睛在两次就诊时进行了测试（两次就诊间隔时间平均为 10[8]天）。每次就诊均包括高对比度 VA，然后在相同照明条件下（亮度为 110cd/m），在同一只眼睛中以习惯矫正的方式进行 12 次随机顺序的 CS 测试（6 种不同的 SpotChecks 和 6 种不同的 Pelli-Robson）。在两次就诊之间的 6 天内，同一只眼睛每天使用一次家用 SpotChecks 进行自我测试。SpotChecks 的评分方法是在最高行上有≥2 个错误的对数 CS。Pelli-Robson 通过 [0.05×正确读取的字母数-0.15] 进行评分。对数 CS 的重复性定义为 1.96 S，S 代表个体内标准差。使用 Bootstrap 假设检验进行重复性比较。

结果

SpotChecks 和 Pelli-Robson 显示出相似的单次就诊或就诊间重复性（p=0.14-0.81）。家用 SpotChecks 的日间重复性为 0.18 对数 CS，与两次就诊中首次使用 SpotChecks 或 Pelli-Robson 时的测量结果相同。通过使用两次重复测量的平均值（p=0.02）或三次重复测量的平均值（p=0.04）来测量 SpotChecks，可将就诊间的重复性提高到 0.15。年龄对 SpotChecks 和 Pelli-Robson 的对数 CS 有轻微影响（每 10 年减少 0.015，p=0.02）。与<50 岁的人相比，≥50 岁的人的平均对数 CS 低 0.05（SpotChecks 为 1.84[0.10]，Pelli-Robson 为 1.77[0.10]）（SpotChecks 为 1.89[0.07]，Pelli-Robson 为 1.83[0.07]）。