Haymes Sharon A, Roberts Kenneth F, Cruess Alan F, Nicolela Marcelo T, LeBlanc Raymond P, Ramsey Michael S, Chauhan Balwantray C, Artes Paul H
Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Canada.
Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2739-45. doi: 10.1167/iovs.05-1419.
To compare the reliability, validity, and responsiveness of the Mars Letter Contrast Sensitivity (CS) Test to the Pelli-Robson CS Chart.
One eye of 47 normal control subjects, 27 patients with open-angle glaucoma, and 17 with age-related macular degeneration (AMD) was tested twice with the Mars test and twice with the Pelli-Robson test, in random order on separate days. In addition, 17 patients undergoing cataract surgery were tested, once before and once after surgery.
The mean Mars CS was 1.62 log CS (0.06 SD) for normal subjects aged 22 to 77 years, with significantly lower values in patients with glaucoma or AMD (P<0.001). Mars test-retest 95% limits of agreement (LOA) were +/-0.13, +/-0.19, and +/-0.24 log CS for normal, glaucoma, and AMD, respectively. In comparison, Pelli-Robson test-retest 95% LOA were +/-0.18, +/-0.19, and +/-0.33 log CS. The Spearman correlation between the Mars and Pelli-Robson tests was 0.83 (P<0.001). However, systematic differences were observed, particularly at the upper-normal end of the range, where Mars CS was lower than Pelli-Robson CS. After cataract surgery, Mars and Pelli-Robson effect size statistics were 0.92 and 0.88, respectively.
The results indicate the Mars test has test-retest reliability equal to or better than the Pelli-Robson test and comparable responsiveness. The strong correlation between the tests provides evidence the Mars test is valid. However, systematic differences indicate normative values are likely to be different for each test. The Mars Letter CS Test is a useful and practical alternative to the Pelli-Robson CS Chart.
比较马尔斯字母对比敏感度（CS）测试与佩利 - 罗布森CS图表的可靠性、有效性和反应性。
对47名正常对照受试者、27名开角型青光眼患者和17名年龄相关性黄斑变性（AMD）患者的一只眼睛，分别在不同日期以随机顺序进行两次马尔斯测试和两次佩利 - 罗布森测试。此外，对17名接受白内障手术的患者在手术前和手术后各进行一次测试。
22至77岁正常受试者的马尔斯CS平均值为1.62 log CS（标准差0.06），青光眼或AMD患者的值显著较低（P<0.001）。马尔斯测试 - 重测95%一致性界限（LOA）对于正常、青光眼和AMD患者分别为±0.13、±0.19和±0.24 log CS。相比之下，佩利 - 罗布森测试 - 重测95% LOA为±0.18、±0.19和±0.33 log CS。马尔斯测试与佩利 - 罗布森测试之间的斯皮尔曼相关性为0.83（P<0.001）。然而，观察到系统差异，特别是在正常范围的上限，此时马尔斯CS低于佩利 - 罗布森CS。白内障手术后，马尔斯和佩利 - 罗布森效应大小统计值分别为0.92和0.88。
结果表明马尔斯测试具有与佩利 - 罗布森测试相当或更好的重测可靠性以及相当的反应性。测试之间的强相关性证明马尔斯测试是有效的。然而，系统差异表明每个测试的标准值可能不同。马尔斯字母CS测试是佩利 - 罗布森CS图表的一种有用且实用的替代方法。
