Geriatric Medicine Research, Dalhousie University & Nova Scotia Health, Halifax, Nova Scotia, Canada.
Department of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Centre de Formation Médicale du Nouveau-Brunswick, Université de Sherbrooke, Moncton, New Brunswick, Canada.
Arch Gerontol Geriatr. 2024 Dec;127:105556. doi: 10.1016/j.archger.2024.105556. Epub 2024 Jul 6.
To examine the association of lifestyle behaviours (LSB) with physical activity (PA) and frailty; also, to examine if associations differ by sex and age.
24,828 individuals [49.6 ± 17.6 years (range: 20-85), 51.6 % female] from the National Health and Nutrition Examination Survey (cycles 2009-2018) were included. Individuals were divided into Active (≥150 min/week of moderate-to-vigorous physical activity (MVPA)) and Inactive (<150 min/week MVPA) based on self-reported PA. Frailty was measured by a 46-item Frailty Index (FI). LSB consisted of stationary time, sleep, diet quality, and alcohol and smoking habits. LSB was summed into a score [0-5]. Linear regression models were used with each LSB in isolation and the summed LSB with frailty.
There were 7,495 (30.1 %) Active and 17,333 (69.8 %) Inactive individuals. The FI was lower in the Active participants (Active: 0.10 ± 0.08; Inactive: 0.15 ± 0.12; p < 0.01). A worse LSB score was associated with an increased FI in all behaviours but females who binge drink and smoke (p-all>0.14). For inactive individuals, all LSBs were associated with an increased FI except those who binge drink and male smokers (p = 0.08). There was a significant association between increased summed LSB and an increased FI (β range: Active, 0.024-0.037; Inactive, 0.028, 0.046. p-all<0.01); the Active group had a lower FI at every age group than the Inactive group (p < 0.001).
PA was associated with a lower FI even among those with a poor LSB score. This association is dependent on age, with older individuals reporting a stronger association.
研究生活方式行为（LSB）与体力活动（PA）和虚弱之间的关系；并探讨这种关系是否因性别和年龄而异。
本研究纳入了 24828 名来自 2009 年至 2018 年全国健康和营养检查调查（NHANES）的个体[年龄（范围：20-85）为 49.6±17.6 岁，女性占 51.6%]。根据自我报告的 PA，个体被分为活跃（每周≥150 分钟的中等到剧烈体力活动（MVPA））和不活跃（每周＜150 分钟 MVPA）。虚弱通过 46 项虚弱指数（FI）来衡量。LSB 包括久坐时间、睡眠、饮食质量、饮酒和吸烟习惯。LSB 得分[0-5]相加。使用线性回归模型分别对每种 LSB 以及相加的 LSB 与虚弱进行分析。
7495 名（30.1%）个体为活跃，17333 名（69.8%）个体为不活跃。活跃组的 FI 较低（活跃组：0.10±0.08；不活跃组：0.15±0.12；p＜0.01）。在所有行为中，较差的 LSB 评分与 FI 增加相关，但在 binge drink 和吸烟的女性中除外（p-all＞0.14）。对于不活跃的个体，除了 binge drink 和男性吸烟者之外，所有 LSB 都与 FI 增加相关（p=0.08）。增加的总和 LSB 与 FI 增加之间存在显著相关性（β范围：活跃组，0.024-0.037；不活跃组，0.028，0.046；p-all＜0.01）；与不活跃组相比，活跃组在每个年龄组的 FI 都较低（p＜0.001）。
即使在 LSB 评分较差的个体中，PA 也与较低的 FI 相关。这种关联取决于年龄，年龄较大的个体报告的关联更强。
