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[实验动物眼前节和后节的同步摄影或血管造影]

[Simultaneous photography or angiography of anterior and posterior eye segments in experimental animals].

作者信息

Baurmann H, Jankolovitz M, Wirmer M, Wolter M, Anda L P, Hörnchen U

出版信息

Klin Monbl Augenheilkd. 1985 Aug;187(2):113-9. doi: 10.1055/s-2008-1051000.

DOI:10.1055/s-2008-1051000
PMID:3903333
Abstract

Simultaneous photographic or angiographic studies of the anterior and posterior segments requires a considerable reduction in the respective parts of the negatives; this can be avoided by simultaneous study of the one segment ipsilaterally and the other contralaterally (this can also be performed vice versa). Differences and common properties of the eyes of rabbits and miniature pigs and the human eye are described. Apart from the monkey eye, the pig eye is most readily comparable with the human eye as regards vasotopographic and vasomorphologic conditions. In addition, the courses of angiographies in the eyes of experimental animals were observed; measurements of fluorescein inflow and circulation times in the anterior and posterior segments in miniature pigs are presented. These were subjected to significance tests: only the difference in the inflow and outflow of the dye in retinal vessels was found to be statistically highly significant. The difference in inflow between choroidal and retinal vessels was not significant, though this may have been due to an error of measurement. The techniques and measurements described represent the basis of observation in miniature pigs with experimentally induced hypertension.

摘要

对眼前段和后段进行同步摄影或血管造影研究需要大幅缩小底片的相应部分;通过同侧研究一个眼段而对侧研究另一个眼段(反之亦然)可避免这种情况。描述了兔眼、小型猪眼与人眼的差异和共同特性。除猴眼外,就血管拓扑学和血管形态学状况而言,猪眼与人眼最具可比性。此外,还观察了实验动物眼内血管造影的过程;给出了小型猪眼前段和后段荧光素流入和循环时间的测量结果。对这些结果进行了显著性检验:仅发现视网膜血管中染料流入和流出的差异具有高度统计学显著性。脉络膜血管和视网膜血管之间的流入差异不显著,不过这可能是测量误差所致。所描述的技术和测量方法是对实验性高血压小型猪进行观察的基础。

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