Department of Neurosurgery, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.
Department of Neurosurgery, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.
Clin Neurophysiol. 2024 Sep;165:166-179. doi: 10.1016/j.clinph.2024.06.015. Epub 2024 Jul 9.
The objective of this narrative review was to locate and assess recent articles employing a combinatorial approach of transcutaneous spinal cord stimulation or epidural spinal cord stimulation with additional modalities. We sought to provide relevant knowledge of recent literature and advance understanding on outcomes reported, to better equip those working in neurorehabilitation and neuromodulation.
Articles were selected and analyzed based on study approach, stimulation parameters, outcome measures, and presence of neurophysiological data to support findings.
This narrative review analyzed 44 recent articles employing a combinatorial approach of transcutaneous spinal cord stimulation or epidural spinal cord stimulation with additional modalities. Our findings showed that limited research exists regarding such combinatorial approaches, particularly when considering modalities beyond activity-based training. There is also limited consistency in neurophysiological and quality of life outcomes.
Articles involving transcutaneous spinal cord stimulation or epidural spinal cord stimulation with other modalities are limited in the current body of literature. Authors noted variety in approach, sample size, and use of participant perspective. Opportunities are present to add high quality research to this body of literature.
Transcutaneous spinal cord stimulation and epidural spinal cord stimulation are emerging in research as viable avenues for targeting improvement of function after traumatic spinal cord injury, particularly when combined with activity-based training. This body of literature demonstrates viable areas for growth from both neurophysiological and functional perspectives. Further, exploration of novel combinatorial approaches holds potential to offer enhanced contributions to clinical and neurophysiological rehabilitation and research.
本叙述性综述的目的是定位和评估最近采用经皮脊髓电刺激或硬膜外脊髓电刺激与其他方式相结合的方法的文章。我们旨在提供最近文献的相关知识，并深入了解报告的结果，以更好地为神经康复和神经调节领域的工作者提供帮助。
根据研究方法、刺激参数、结果测量以及神经生理学数据的存在来选择和分析文章，以支持研究发现。
本叙述性综述分析了 44 篇最近采用经皮脊髓电刺激或硬膜外脊髓电刺激与其他方式相结合的方法的文章。我们的研究结果表明，关于这种组合方法的研究有限，特别是在考虑超越活动训练的方式时。神经生理学和生活质量结果也缺乏一致性。
涉及经皮脊髓电刺激或硬膜外脊髓电刺激与其他方式相结合的文章在当前文献中有限。作者注意到方法、样本量和参与者观点的多样性。为了丰富这方面的文献，有机会进行高质量的研究。
经皮脊髓电刺激和硬膜外脊髓电刺激在创伤性脊髓损伤后功能改善的研究中崭露头角，特别是与活动训练相结合时。从神经生理学和功能角度来看，这一文献证明了有可行的增长领域。此外，探索新的组合方法有可能为临床和神经生理学康复及研究做出更有价值的贡献。
