Barros Adilia Maria Soares Porciuncula, Pereira Gabrielly Santos, da Silva Josie Resende Torres, da Silva Marcelo Lourenço, da Costa E Silva Maria do Desterro, Ferrera Luciano Maia Alves
Alagoas State University of Health Sciences (UNCISAL), Maceió, Brazil.
Laboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Brazil.
Front Pain Res (Lausanne). 2025 Jul 22;6:1620289. doi: 10.3389/fpain.2025.1620289. eCollection 2025.
Chronic pain affects a significant portion of the population, and conventional treatments often prove insufficient. Spinal Cord Stimulation (SCS), a neuromodulation technique, has shown benefits in pain relief, while physiotherapy is widely employed to enhance physical function and quality of life. Although the combination of these approaches may offer synergistic effects, existing evidence is limited and fragmented.
This systematic review aimed to evaluate the clinical outcomes of Spinal Cord Stimulation (SCS), with or without the association of physiotherapy, in the management of chronic pain in adults. Methodology: The review was conducted following PRISMA guidelines and the PICO strategy. A comprehensive search was performed across databases including Cochrane Library, ScienceDirect, BASE, and VHL (BVS: MEDLINE, IBECS, WPRIM, LILACS, PERIÓDICO CAPES) using MeSH terms and Boolean operators: ("Spinal Cord Stimulation" OR "Neuromodulation") AND ("Chronic Pain" OR "Pain Management") AND ("Physical Therapy Modalities" OR "Physiotherapy" OR "Rehabilitation"). Only studies published in English, Spanish, or Portuguese in the past 10 years were included, focusing on chronic pain and reporting outcomes related to pain reduction and functional improvement.
Eight studies comprising 777 patients were included. Spinal cord stimulation alone led to significant pain reductions, with responder rates above 80% and average decreases of 5-6 cm on pain scales. Improvements in quality of life and functional disability were also reported, with reductions of over 30 points in disability indices and up to 40% in opioid use. However, only one study included physiotherapy as a complementary intervention, without isolating its effects. No study directly evaluated the combined efficacy of SCS and physiotherapy, highlighting a gap in the literature.
The findings highlight the proven effectiveness of SCS in chronic pain management but reveal a lack of studies assessing its integration with physiotherapy. Future clinical trials should address this gap to explore potential synergistic effects and optimize interdisciplinary pain treatment strategies.
慢性疼痛影响着相当一部分人群,传统治疗方法往往效果不佳。脊髓刺激(SCS)作为一种神经调节技术,已显示出在缓解疼痛方面的益处,而物理治疗则广泛用于改善身体功能和生活质量。尽管这些方法的联合应用可能会产生协同效应,但现有证据有限且零散。
本系统评价旨在评估脊髓刺激(SCS)联合或不联合物理治疗在成人慢性疼痛管理中的临床效果。方法:本评价按照PRISMA指南和PICO策略进行。使用医学主题词(MeSH)和布尔运算符在多个数据库中进行全面检索,包括Cochrane图书馆、ScienceDirect、BASE和VHL(BVS:MEDLINE、IBECS、WPRIM、LILACS、PERIÓDICO CAPES):(“脊髓刺激”或“神经调节”)且(“慢性疼痛”或“疼痛管理”)且(“物理治疗方式”或“物理治疗”或“康复”)。仅纳入过去10年以英文、西班牙文或葡萄牙文发表的研究,重点关注慢性疼痛并报告与疼痛减轻和功能改善相关的结果。
纳入了八项研究,共777例患者。单独使用脊髓刺激可显著减轻疼痛,缓解率超过80%,疼痛量表平均下降5 - 6厘米。还报告了生活质量和功能障碍的改善,残疾指数降低超过30分,阿片类药物使用减少高达40%。然而,只有一项研究将物理治疗作为辅助干预措施,但未单独分离其效果。没有研究直接评估SCS与物理治疗的联合疗效,这突出了文献中的空白。
研究结果突出了SCS在慢性疼痛管理中的已证实有效性,但揭示了缺乏评估其与物理治疗整合的研究。未来的临床试验应填补这一空白,以探索潜在的协同效应并优化跨学科疼痛治疗策略。